177750-08-2

Basic information

• Product Name: Acetamide, N-[1-(4-methylphenyl)ethenyl]-
• CAS NO: 177750-08-2
• Molecular Formula: C11H13NO
• Molecular Weight: 175.23
• Mol File: 177750-08-2.mol
• Article Data: 30

Chemical Properties

• Boiling Point: 372.5±35.0 °C(Predicted)
• Density: 1.007±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Acetamide, N-[1-(4-methylphenyl)ethenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Acetamide, N-[1-(4-methylphenyl)ethenyl]-(177750-08-2)
• EPA Substance Registry System: Acetamide, N-[1-(4-methylphenyl)ethenyl]-(177750-08-2)

Safety Data

• Hazardous Substances Data: 177750-08-2(Hazardous Substances Data)

Upstream product

• 2089-33-0 4-methylacethophenone oxime 
• 108-24-7 acetic anhydride 
• 64-19-7 acetic acid 
• 91633-31-7 1-(para-methylphenyl)-1-azidoethane 
• 536-74-3 phenylacetylene 
• 122-00-9 para-methylacetophenone 
• 917-64-6 methyl magnesium iodide 
• 104-85-8 para-methylbenzonitrile 
• 5202-78-8 acetylaminoethylene 
• 106-38-7 para-bromotoluene 
• 536-50-5 CH₃C₆H₄CH(CH₃)OH 
• 91854-79-4 1-imino-1-(p-methylphenyl)ethane 

Downstream Products

• 92520-13-3 N-(1-(4-methylphenyl)ethyl)acetamide 
• 960371-74-8 bis(4-methoxyphenyl) (R)-2-(4-oxo-4-p-tolylbutan-2-yl)malonate 
• 1251575-59-3 C₁₇H₁₇NO₂S 
• 1620165-29-8 (Z)-N-(1-(p-tolyl)-4-(triisopropylsilyl)but-1-en-3-yn-1-yl)acetamide 
• 868602-86-2 N-methyl-N-(1-(p-tolyl)vinyl)acetamide 
• 1392296-72-8 N-benzyl-N-(1-(p-tolyl)vinyl)acetamide 
• 1174133-34-6 ethyl 6-methyl-4-(p-tolyl)quinoline-2-carboxylate 
• 68185-01-3 ethyl 2-acetamido-2-(p-tolylamino)acetate 

Relevant articles and documents

Fe(III)-catalyzed Oxidative Povarov Reaction with Molecular Oxygen Oxidant

The synthesis of tetrahydroquinoline derivatives from dimethyl anilines and enamides has been developed by Fe(III)-phenanthroline complex under aerobic condition. The oxidation of tertiary anilines involving a single electron transfer of Fe(phen)3(PF6)3 afforded the iminium ion intermediate, which reacted with electron-rich alkenes to build a six-membered N-heterocycles containing quaternary carbon center via the oxidative Povarov reaction process.

Rhodium(III)-Catalyzed Direct C-H Arylation of Various Acyclic Enamides with Arylsilanes

The stereoselective β-C(sp2)-H arylation of various acyclic enamides with arylsilanes via Rh(III)-catalyzed cross-coupling reaction was illustrated. The methodology was characterized by extraordinary efficacy and stereoselectivity, a wide scope of substrates, good functional group tolerance, and the adoption of environmentally friendly arylsilanes. The utility of this present method was evidenced by the gram-scale synthesis and further elaboration of the product. In addition, Rh(III)-catalyzed C-H activation is considered to be the critical step in the reaction mechanism.

Asymmetric Full Saturation of Vinylarenes with Cooperative Homogeneous and Heterogeneous Rhodium Catalysis

Homogeneous and heterogeneous catalyzed reactions can seldom operate synergistically under the same conditions. Here we communicate the use of a single rhodium precursor that acts in both the homogeneous and heterogeneous phases for the asymmetric full saturation of vinylarenes that, to date, constitute an unmet bottleneck in the field. A simple asymmetric hydrogenation of a styrenic olefin, enabled by a ligand accelerated effect, accounted for the facial selectivity in the consecutive arene hydrogenation. Tuning the ratio between the phosphine ligand and the rhodium precursor controlled the formation of homogeneous and heterogeneous catalytic species that operate without interference from each other. The system is flexible in terms of both the chiral ligand and the nature of the external olefin. We anticipate that our findings will promote the development of asymmetric arene hydrogenations.