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177839-89-3

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177839-89-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 177839-89-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,7,8,3 and 9 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 177839-89:
(8*1)+(7*7)+(6*7)+(5*8)+(4*3)+(3*9)+(2*8)+(1*9)=203
203 % 10 = 3
So 177839-89-3 is a valid CAS Registry Number.

177839-89-3Relevant articles and documents

Practical asymmetric synthesis of Sitagliptin phosphate monohydrate

Gao, Haoling,Yu, Jiangang,Ge, Chengsheng,Jiang, Qun

, (2018)

Optically pure sitagliptin phosphate monohydrate is efficiently and practically synthesized through a chiral hemiacetal as the key intermediate in 54% overall yield starting from (E)-4-(2,4,5-trifluorophenyl)but-2-enal and N-boc-protected hydroxylamine. The chiral hemiacetal fragment is constructed by a tandem aza-Michael/hemiacetal reaction catalyzed by an organocatalyst and the influence of acidity of Br?nsted acid on tandem aza-Michael/hemiacetal reaction is researched in detail.

Inhibitors of farnesyl protein transferase

-

, (2008/06/13)

Disclosed are quinoline and benzazepine derivatives that inhibit farnesyl-protein transferase (FTase) and the farnesylation of the oncogenic protein Ras. Thus, the compounds are useful as anti-cancer agents. The compounds are also useful in the treatment of diseases other than cancer.

A novel approach to homochiral β-amino acids 1

Seki, Masahiko,Matsumoto, Kazuo

, p. 3165 - 3168 (2007/10/03)

An efficient synthesis of γ-aryl or alkyl substituted β-amino acids starting from N-Cbz-L-homoserine lactone via the formation of α-amino aryl, alkenyl or alkynyl ketones with the original α-carbon chirality retained as such is described. Copyright

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