177949-64-3

Basic information

• Product Name: Acetic acid (2R,3R,4R,5R)-4-acetoxy-5-acetoxymethyl-2-(2-acetylamino-6-p-tolylamino-purin-9-yl)-tetrahydro-furan-3-yl ester
• Synonyms: Acetic acid (2R,3R,4R,5R)-4-acetoxy-5-acetoxymethyl-2-(2-acetylamino-6-p-tolylamino-purin-9-yl)-tetrahydro-furan-3-yl ester
• CAS NO: 177949-64-3
• Molecular Weight: 540.533
• Mol File: 177949-64-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Acetic acid (2R,3R,4R,5R)-4-acetoxy-5-acetoxymethyl-2-(2-acetylamino-6-p-tolylamino-purin-9-yl)-tetrahydro-furan-3-yl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Acetic acid (2R,3R,4R,5R)-4-acetoxy-5-acetoxymethyl-2-(2-acetylamino-6-p-tolylamino-purin-9-yl)-tetrahydro-furan-3-yl ester(177949-64-3)
• EPA Substance Registry System: Acetic acid (2R,3R,4R,5R)-4-acetoxy-5-acetoxymethyl-2-(2-acetylamino-6-p-tolylamino-purin-9-yl)-tetrahydro-furan-3-yl ester(177949-64-3)

Safety Data

• Hazardous Substances Data: 177949-64-3(Hazardous Substances Data)

Upstream product

• 106-49-0 p-toluidine 
• 385806-09-7 Acetic acid (2R,3R,4R,5R)-4-acetoxy-5-acetoxymethyl-2-(2-acetylamino-6-bromo-purin-9-yl)-tetrahydro-furan-3-yl ester 
• 30747-23-0 Acetic acid (2R,3R,4R,5R)-4-acetoxy-5-acetoxymethyl-2-(2-acetylamino-6-oxo-1,6-dihydro-purin-9-yl)-tetrahydro-furan-3-yl ester 

Relevant articles and documents

Transformations of thiopyrimidine and thiopurine nucleosides following oxidation with dimethyldioxirane

A general and convenient method for the synthesis of several pyrimidine and purine nucleosides by selective oxidation of thionucleosides with dimethyldioxirane is reported. Thioketo moieties in the C-4 position of the pyrimidine ring, and in the C-6, and C-8 positions of the purine ring are the domain of oxidative nucleophilic substitution. Thioketo moieties in the C-2 position of both purine and pyrimidine rings are the domain of desulfurization or formation of disulfides.