17812-38-3 Usage
Description
(2S)-6β-(3-Furyl)-α,α,3α-trimethylpiperidine-2β-(1-propanol) is a piperidine derivative featuring a unique structural composition. This cyclic amine contains a six-membered ring with a furan group—a five-membered aromatic ring with one oxygen atom—attached at the 6β position. Additionally, a 1-propanol group is connected to the 2β position of the piperidine ring, and three methyl groups are present at the 2α, 3α, and 6β positions. The distinctive arrangement of these functional groups may endow the compound with specific properties, making it a candidate for applications in pharmaceutical or industrial fields.
Uses
Used in Pharmaceutical Industry:
(2S)-6β-(3-Furyl)-α,α,3α-trimethylpiperidine-2β-(1-propanol) is used as a potential pharmaceutical agent for its unique structural features. The combination of the furan and 1-propanol groups, along with the methyl groups, may contribute to its interaction with biological targets, offering possible applications in the development of new drugs.
Used in Industrial Applications:
In the industrial sector, (2S)-6β-(3-Furyl)-α,α,3α-trimethylpiperidine-2β-(1-propanol) may serve as a building block or intermediate in the synthesis of various chemical products. Its specific structural elements could be leveraged to create novel materials or compounds with tailored properties for specialized uses.
Check Digit Verification of cas no
The CAS Registry Mumber 17812-38-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,7,8,1 and 2 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 17812-38:
(7*1)+(6*7)+(5*8)+(4*1)+(3*2)+(2*3)+(1*8)=113
113 % 10 = 3
So 17812-38-3 is a valid CAS Registry Number.
17812-38-3Relevant articles and documents
A short and enantiospecific synthesis of (-)-nupharamine
Gebauer, Julian,Blechert, Siegfried
, p. 2826 - 2828 (2005)
A short and convergent synthesis of the naturally occurring sesquiterpenoid piperidine alkaloid (-)-nupharamine is presented starting from (-)-isopinocampheol via cross metathesis and reductive amination as the key steps. Georg Thieme Verlag Stuttgart.
Synthesis of two nuphar alkaloids by allenic hydroxylamine cyclisation
Bates, Roderick W.,Lim, Chia Juan
scheme or table, p. 866 - 868 (2010/06/11)
A highly diastereoselective silver-catalysed cyclisation of a 2-substituted β-allenic hydroxylamine is reported. The resulting trans-isoxazolidine is converted into two Nuphar alkaloids by a sequence involving cross-metathesis and intramolecular reductive amination. Georg Thieme Verlag Stuttgart - New York.
Total synthesis of (-)-nupharamine and (+)-3-epinupharamine via asymmetric nitroso Diels-Alder reaction
Aoyagi, Sakae,Shishido, Yuji,Kibayashi, Chihiro
, p. 4325 - 4328 (2007/10/02)
Chiral synthesis of (-)-nupharamine and (+)-3-epinupharamine, based on elaboration of the intramolecular asymmetric Diels-Alder reaction of N-acylnitroso compounds and the introduction of the furyl group in a fully stereocontrolled manner, is described.
