178483-03-9

Basic information

• Product Name: 3-Phenyl-pyrrolidine-1-carboxylic acid methyl ester
• Synonyms: 3-Phenyl-pyrrolidine-1-carboxylic acid methyl ester
• CAS NO: 178483-03-9
• Molecular Weight: 205.257
• Mol File: 178483-03-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-Phenyl-pyrrolidine-1-carboxylic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Phenyl-pyrrolidine-1-carboxylic acid methyl ester(178483-03-9)
• EPA Substance Registry System: 3-Phenyl-pyrrolidine-1-carboxylic acid methyl ester(178483-03-9)

Safety Data

• Hazardous Substances Data: 178483-03-9(Hazardous Substances Data)

Upstream product

• 63603-33-8 2,5-dihydropyrrole-1-carboxylic acid methyl ester 
• 178482-86-5 3-Phenyl-2,3-dihydro-pyrrole-1-carboxylic acid methyl ester 

Downstream Products

• 936-44-7 3-phenylpyrrolidine 

Relevant articles and documents

Regioselective synthesis of 3-aryl substituted pyrrolidines via palladium catalyzed arylation: Pharmacological evaluation for central dopaminergic and serotonergic activity

A series of 3-arylpyrrolidines has been synthesised via palladium catalyzed arylation and evaluated for dopaminergic and serotonergic activity in vitro and in vivo. Compounds substituted by electron withdrawing groups on the meta position of the aromatic ring, were found to be preferential dopamine autoreceptor antagonists.