178876-83-0 Usage
General Description
Methyl 6-amino-3-bromopicolinate is a chemical compound with the molecular formula C7H7BrN2O2. It is a derivative of picolinic acid, containing a bromine atom and an amino group. Methyl 6-amino-3-bromopicolinate is commonly used in organic synthesis and medicinal chemistry as a building block for the preparation of various pharmaceuticals and biologically active molecules. It can undergo various chemical reactions such as nucleophilic substitution, metal-catalyzed coupling, and condensation reactions to form more complex organic compounds. Methyl 6-amino-3-bromopicolinate has potential applications in the development of new drugs, agrochemicals, and other fine chemicals due to its versatile reactivity and structural properties.
Check Digit Verification of cas no
The CAS Registry Mumber 178876-83-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,8,8,7 and 6 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 178876-83:
(8*1)+(7*7)+(6*8)+(5*8)+(4*7)+(3*6)+(2*8)+(1*3)=210
210 % 10 = 0
So 178876-83-0 is a valid CAS Registry Number.
InChI:InChI=1/C7H7BrN2O2/c1-12-7(11)6-4(8)2-3-5(9)10-6/h2-3H,1H3,(H2,9,10)
178876-83-0Relevant articles and documents
HPK1 ANTAGONISTS AND USES THEREOF
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Paragraph 0801; 0802, (2021/03/19)
The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of HPK1, and the treatment of HPK1-mediated disorders.
APOPTOSIS-INDUCED AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES
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Paragraph 1079, (2013/04/24)
Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-xL proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-xL protein.
GAMMA SECRETASE MODULATORS
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Page/Page column 61-62, (2011/08/08)
The invention relates to compounds of formula wherein R1, R1′, R2, R3, n, A, and hetaryl are defined herein or to pharmaceutically active acid addition salts thereof. The present compounds of formula I are modulators for amyloid beta and thus, they may be useful for the treatment or prevention of a disease associated with the deposition of β-amyloid in the brain, in particular Alzheimer's disease, and other diseases such as cerebral amyloid angiopathy, hereditary cerebral hemorrhage with amyloidosis, Dutch-type (HCHWA-D), multi-infarct dementia, dementia pugilistica and Down syndrome.
