178896-78-1

Basic information

• Product Name: 6-(trifluoromethyl)-5-methoxy-1H-indole
• Synonyms: 6-(trifluoromethyl)-5-methoxy-1H-indole;5-Methoxy-6-(trifluoroMethyl)-1H-indole;5-Methoxy-6-(trifluoromethyl)indole;6-Trifluoromethyl-5-methoxyindole
• CAS NO: 178896-78-1
• Molecular Formula: C₁₀H₈F₃NO
• Molecular Weight: 215.173
• Mol File: 178896-78-1.mol
• Article Data: 7

Chemical Properties

• Melting Point: 104℃
• Appearance: /
• Density: 1.350
• CAS DataBase Reference: 6-(trifluoromethyl)-5-methoxy-1H-indole(CAS DataBase Reference)
• NIST Chemistry Reference: 6-(trifluoromethyl)-5-methoxy-1H-indole(178896-78-1)
• EPA Substance Registry System: 6-(trifluoromethyl)-5-methoxy-1H-indole(178896-78-1)

Safety Data

• Hazard Codes: T
• Statements: 25-36
• Safety Statements: 26-45
• RIDADR: UN 2811 6.1 / PGIII
• WGK Germany: 3
• Hazardous Substances Data: 178896-78-1(Hazardous Substances Data)

Usage

Description

6-(trifluoromethyl)-5-methoxy-1H-indole is an organic compound that belongs to the indole family. It is characterized by the presence of a trifluoromethyl group at the 6th position and a methoxy group at the 5th position of the indole ring. 6-(trifluoromethyl)-5-methoxy-1H-indole is known for its potential applications in various fields due to its unique chemical structure and properties.

Uses

Used in Pharmaceutical Industry:
6-(trifluoromethyl)-5-methoxy-1H-indole is used as a reactant for the preparation of pyridylcarbamoylindolines, which are selective 5HT2C/2B receptor antagonists. These antagonists play a crucial role in the development of medications targeting various neurological and psychiatric disorders, such as schizophrenia, anxiety, and depression. The compound's unique structure allows for the creation of potent and selective antagonists, making it a valuable asset in the pharmaceutical industry.

Upstream product

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Relevant articles and documents

SUBSTITUTED INDOLINE DERIVATIVES AS DENGUE VIRAL REPLICATION INHIBITORS

The present invention relates to substituted indoline derivatives, methods to prevent or treat dengue viral infections by using said compounds and also relates to said compounds for use as a medicine, more preferably for use as a medicine to treat or prevent dengue viral infections. The present invention furthermore relates to pharmaceutical compositions or combination preparations of the compounds, to the compositions or preparations for use as a medicine, more preferably for the prevention or treatment of dengue viral infections. The invention also relates to processes for preparation of the compounds.

SUBSTITUTED INDOLINE DERIVATIVES AS DENGUE VIRAL REPLICATION INHIBITORS

The present invention concerns substituted indoline derivatives, methods to prevent or treat dengue viral infections by using said compounds and also relates to said compounds for use as a medicine, more preferably for use as a medicine to treat or prevent dengue viral infections. The present invention furthermore relates to pharmaceutical compositions or combination preparations of the compounds, to the compositions or preparations for use as a medicine, more preferably for the prevention or treatment of dengue viral infections. The invention also relates to processes for preparation of the compounds.

SUBSTITUTED INDOLINE DERIVATIVES AS DENGUE VIRAL REPLICATION INHIBITORS

The present invention concerns substituted indoline compounds, methods to prevent or treat dengue viral infections by using said compounds and also relates to said compounds for use as a medicine, more preferably for use as a medicine to treat or prevent