179077-79-3

Basic information

• Product Name: ((R)-2-Phenyl-1-thiazol-2-yl-ethyl)-[(1R,4R)-1,7,7-trimethyl-bicyclo[2.2.1]hept-(2E)-ylidene]-amine
• Synonyms: ((R)-2-Phenyl-1-thiazol-2-yl-ethyl)-[(1R,4R)-1,7,7-trimethyl-bicyclo[2.2.1]hept-(2E)-ylidene]-amine
• CAS NO: 179077-79-3
• Molecular Weight: 338.517
• Mol File: 179077-79-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ((R)-2-Phenyl-1-thiazol-2-yl-ethyl)-[(1R,4R)-1,7,7-trimethyl-bicyclo[2.2.1]hept-(2E)-ylidene]-amine(CAS DataBase Reference)
• NIST Chemistry Reference: ((R)-2-Phenyl-1-thiazol-2-yl-ethyl)-[(1R,4R)-1,7,7-trimethyl-bicyclo[2.2.1]hept-(2E)-ylidene]-amine(179077-79-3)
• EPA Substance Registry System: ((R)-2-Phenyl-1-thiazol-2-yl-ethyl)-[(1R,4R)-1,7,7-trimethyl-bicyclo[2.2.1]hept-(2E)-ylidene]-amine(179077-79-3)

Safety Data

• Hazardous Substances Data: 179077-79-3(Hazardous Substances Data)

Upstream product

• 100-39-0 benzyl bromide 
• 179077-74-8 (1R,4R)-2-(thiazol-2-ylmethylimino)bornane 

Downstream Products

• 144775-04-2 Boc-(R)-dolaphenine 
• 77119-85-8 N-(tert-butoxycarbonyl)-D-phenylalaninal 
• 144774-97-0 [R-(-)-2-phenyl-1-(2-thiazolyl)ethylamine] 

Relevant articles and documents

Alkylation of camphor and pinanone imines of 2-(aminomethyl)thiazole. Enantioselective synthesis of 2-(1-aminoalkyl)thiazoles

A method is described for the enantioselective synthesis of 2-(1-aminoalkyl)thiazoles 6 via stereoselective alkylation of the carbanions of (+)-(R)-camphor and (-)-(1S, 2S, 5S)-2-hydroxypinan-3-one imines 2 and 3 derived from 2-(aminomethyl)thiazole (2-AMT, 1). Compounds 6 serve as α-amino aldehyde precursors via thiazolyl-to-formyl conversion.