179118-73-1 Usage
Description
Acebrophylline is a bronchodilator and mucolytic medication, a combination of theophylline and its derivative ambroxol, used for the treatment of respiratory conditions such as chronic obstructive pulmonary disease (COPD) and asthma. It functions by relaxing the muscles in the airways to facilitate breathing and reducing mucus viscosity for easier clearance from the lungs. Acebrophylline is available in tablet and syrup forms and is generally well-tolerated, with potential side effects including gastrointestinal disturbances, headache, and dizziness. It should be used under the guidance of a healthcare professional due to possible interactions with other medications and contraindications in certain medical conditions.
Uses
Used in Respiratory Medicine:
Acebrophylline is used as a bronchodilator and mucolytic agent for the treatment of chronic obstructive pulmonary disease (COPD) and asthma. It aids in relaxing the airway muscles, making breathing easier, and in reducing the viscosity of mucus, facilitating its clearance from the lungs.
Used in Pharmaceutical Formulations:
Acebrophylline is used in the development of tablet and syrup formulations to provide relief for respiratory conditions. These formulations are designed for ease of administration and to ensure the medication reaches the target areas in the respiratory system effectively.
Check Digit Verification of cas no
The CAS Registry Mumber 179118-73-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,9,1,1 and 8 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 179118-73:
(8*1)+(7*7)+(6*9)+(5*1)+(4*1)+(3*8)+(2*7)+(1*3)=161
161 % 10 = 1
So 179118-73-1 is a valid CAS Registry Number.
InChI:InChI=1/C13H18Br2N2O.C9H10N4O4/c14-9-5-8(13(16)12(15)6-9)7-17-10-1-3-11(18)4-2-10;1-11-7-6(8(16)12(2)9(11)17)13(4-10-7)3-5(14)15/h5-6,10-11,17-18H,1-4,7,16H2;4H,3H2,1-2H3,(H,14,15)
179118-73-1Relevant articles and documents
A PROCESS FOR THE PREPARATION OF ACEBROPHYLLINE
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Page/Page column 6-7, (2014/06/11)
The present invention relates to an improved process for preparing Acebrophylline comprising preparing a reaction mixture of theophylline-7-acetate and ambroxol base in a non-polar solvent; heating said reaction mixture at a suitable temperature; and isolating Acebrophylline by filtration. The yield of Acebrophylline is between 95-98 % with a purity of 99%.