179410-97-0

Basic information

• Product Name: 1,5-Benzothiazepin-8-ol, 7-bromo-3-butyl-3-ethyl-2,3,4,5-tetrahydro-5-phenyl-, 1,1-dioxide
• CAS NO: 179410-97-0
• Molecular Formula: C21H26BrNO3S
• Molecular Weight: 452.412
• Mol File: 179410-97-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1,5-Benzothiazepin-8-ol, 7-bromo-3-butyl-3-ethyl-2,3,4,5-tetrahydro-5-phenyl-, 1,1-dioxide(CAS DataBase Reference)
• NIST Chemistry Reference: 1,5-Benzothiazepin-8-ol, 7-bromo-3-butyl-3-ethyl-2,3,4,5-tetrahydro-5-phenyl-, 1,1-dioxide(179410-97-0)
• EPA Substance Registry System: 1,5-Benzothiazepin-8-ol, 7-bromo-3-butyl-3-ethyl-2,3,4,5-tetrahydro-5-phenyl-, 1,1-dioxide(179410-97-0)

Safety Data

• Hazardous Substances Data: 179410-97-0(Hazardous Substances Data)

Upstream product

• 591-50-4 iodobenzene 

Downstream Products

• 179410-96-9 7-bromo-3-n-Butyl-3-ethyl-2,3,4,5-tetrahydro-8-methoxy-5-phenyl-1,5-benzothiazepine-1,1-dioxide 
• 358376-02-0 3-butyl-3-ethyl-8-hydroxy-7-(methylthio)-5-phenyl-2,3,4,5-tetrahydro-1,5-benzothiazepine 1,1-dioxide 

Relevant articles and documents

BENZOTHIA(DI)AZEPINE COMPOUNDS AND THEIR USE AS BILE ACID MODULATORS

The invention relates to 1,5-benzothiazepine and 1,2,5-benzothiadiazepine derivatives of formula (I). These compounds are bile acid modulators having apical sodium-dependent bile acid transporter (ASBT) and/or liver bile acid transport (LBAT) inhibitory activity. The invention also relates to pharmaceutical compositions comprising these compounds and to the use of these compounds in the treatment of cardiovascular diseases, fatty acid metabolism and glucose utilization disorders, gastrointestinal diseases and liver diseases.