179420-75-8

Basic information

• Product Name: 1-(4-Iodo-phenyl)-2-methyl-1H-imidazole
• Synonyms: 1-(4-Iodo-phenyl)-2-methyl-1H-imidazole
• CAS NO: 179420-75-8
• Molecular Formula: C₁₀H₉IN₂
• Molecular Weight: 284.1
• Mol File: 179420-75-8.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1-(4-Iodo-phenyl)-2-methyl-1H-imidazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-Iodo-phenyl)-2-methyl-1H-imidazole(179420-75-8)
• EPA Substance Registry System: 1-(4-Iodo-phenyl)-2-methyl-1H-imidazole(179420-75-8)

Safety Data

• Hazardous Substances Data: 179420-75-8(Hazardous Substances Data)

Usage

Description

1-(4-Iodo-phenyl)-2-methyl-1H-imidazole is a heterocyclic aromatic organic compound with the molecular formula C9H8IN3. It features an imidazole ring with a 4-iodo-phenyl group and a methyl group attached, making it a white to off-white crystalline solid that is slightly soluble in water and soluble in organic solvents.

Uses

Used in Medicinal Chemistry:
1-(4-Iodo-phenyl)-2-methyl-1H-imidazole is used as a building block for the development of pharmaceutical drugs due to its potential pharmacological properties.
Used in Organic Synthesis:
1-(4-Iodo-phenyl)-2-methyl-1H-imidazole is also utilized in organic synthesis, serving as a key intermediate for the creation of various organic compounds.
Used in Chemical Research and Development:
1-(4-Iodo-phenyl)-2-methyl-1H-imidazole may be employed in the field of chemical research and development for exploring its properties and applications further.

Upstream product

• 693-98-1 2-methylimidazole 
• 352-34-1 4-fluoro-1-iodobenzene 

Downstream Products

• 179420-53-2 ethyl 4-{3-[4-(2-methyl-1H-imidazol-1-yl)phenylthio]phenyl}-3,4,5,6-tetrahydro-2H-pyran-4-carboxylate 
• 179420-17-8 4-[3-[4-(2-methylimidazol-1-yl)phenylthio]phenyl]-3,4,5,6-tetrahydro-2H-pyran-4-carboxamide 
• 179420-35-0 4-{5-fluoro-3-[4-(2-methyl-1H-imidazol-1-yl)phenylthio]phenyl}-3,4,5,6-tetrahydro-2H-pyran-4-carboxamide 
• 179420-54-3 4-{3-[4-(2-methyl-1H-imidazol-1-yl)phenylthio]phenyl}-3,4,5,6-tetrahydro-2H-pyran-4-carboxylic acid 
• 278183-73-6 4-cyano-4-{3-[4-(2-methyl-1H-imidazol-1-yl)phenylthio]}phenyl-3,4,5,6-tetrahydro-2H-pyran 
• 179420-34-9 4-cyano-4-{5-fluoro-3-[4-(2-methyl-1H-imidazol-1-yl)phenylthio]phenyl}-3,4,5,6-tetrahydro-2H-pyran 
• 189277-92-7 (1S,3R,5R)-3-{3-[4-(2-Methyl-imidazol-1-yl)-phenylsulfanyl]-phenyl}-8-oxa-bicyclo[3.2.1]octane-3-carbonitrile 

Relevant articles and documents

Optimization of imidazole 5-lipoxygenase inhibitors and selection and synthesis of a development candidate

Structural modification of imidazole 5-lipoxygenase (5-LO) inhibitors for optimizing inhibitory potency, pharmacokinetic behavior and toxicity (ocular) profile led to 4-{3-[4-(2-methyl-1H-imidazol-1-yl)phenylthio]}phenyl-3,4,5,6- tetrahydro-2H-pyran-4-car

5-lipoxygenase inhibitors

Novel compounds having the ability to inhibit 5-lipoxygenase enzyme and having the following formula I: STR1 and the pharmaceutically acceptable salts thereof, wherein Ar1 is a heterocyclic moiety which is selected from imidazolyl, pyrrolyl, py