179421-14-8

Basic information

• Product Name: 4-cyano-4-(3-iodophenyl)-3,4,5,6-tetrahydro-2H-pyran
• Synonyms: 4-cyano-4-(3-iodophenyl)-3,4,5,6-tetrahydro-2H-pyran
• CAS NO: 179421-14-8
• Molecular Weight: 313.138
• Mol File: 179421-14-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4-cyano-4-(3-iodophenyl)-3,4,5,6-tetrahydro-2H-pyran(CAS DataBase Reference)
• NIST Chemistry Reference: 4-cyano-4-(3-iodophenyl)-3,4,5,6-tetrahydro-2H-pyran(179421-14-8)
• EPA Substance Registry System: 4-cyano-4-(3-iodophenyl)-3,4,5,6-tetrahydro-2H-pyran(179421-14-8)

Safety Data

• Hazardous Substances Data: 179421-14-8(Hazardous Substances Data)

Upstream product

• 14937-45-2 cetyltributylphosphonium bromide 
• 111-44-4 3-oxa-1,5-dichloropentane 
• 130723-54-5 (3-iodophenyl)acetonitrile 

Downstream Products

• 179421-15-9 4-cyano-4-{3-[tri-(1-methylethyl)]silylthiophenyl}-3,4,5,6-tetrahydro-2H-pyran 
• 179420-47-4 methyl 4-[3-[4-(2-methylimidazol-1-yl)phenylthio]phenyl]-3,4,5,6-tetrahydro-2H-pyran-4-carboxylate 
• 179421-20-6 [4-[3-[4-(2-Methylimidazol-1-yl)phenylthio]phenyl]-3,4,5,6-tetrahydro2H-pyran-4yl]methanol 
• 179420-48-5 4-[3-[4(2-Methylimidazol-1-yl)phenylthio]phenyl]-3,4,5,6-tetrahydro-2H-pyran-4-carbaldehyde 
• 179421-18-2 4-(3-Iodophenyl)-3,4,5,6-tetrahydro-2H-pyran-4-carbadehyde 
• 179420-17-8 4-[3-[4-(2-methylimidazol-1-yl)phenylthio]phenyl]-3,4,5,6-tetrahydro-2H-pyran-4-carboxamide 
• 278183-73-6 4-cyano-4-{3-[4-(2-methyl-1H-imidazol-1-yl)phenylthio]}phenyl-3,4,5,6-tetrahydro-2H-pyran 
• 179420-40-7 4-[3-(4-[1,2,4]triazol-4-yl-phenylsulfanyl)-phenyl]-tetrahydro-pyran-4-carbonitrile 

Relevant articles and documents

5-Lipoxygenase inhibitors: Convenient synthesis of 4-[3-(4- heterocyclylphenylthio)phenyl]-3,4,5,6-tetrahydro-2H-pyran-4-carboxamide analogues

A convenient synthetic route to 4-[3-(4-heterocyclylphenylthio)phenyl]-3,4, 5,6-tetrahydro-2H-pyran-4-carboxamide analogues as 5-LO inhibitors is described. This methodology enabled rapid development of structure-activity relationships (SARs) leading to i

5-lipoxygenase inhibitors

Novel compounds having the ability to inhibit 5-lipoxygenase enzyme and having the following formula I: STR1 and the pharmaceutically acceptable salts thereof, wherein Ar1 is a heterocyclic moiety which is selected from imidazolyl, pyrrolyl, py