179473-54-2

Basic information

• Product Name: methyl 6-fluoro-3-methyl-2-(4-phenyl-1-indolinyl)quinoline-4-carboxylate
• Synonyms: methyl 6-fluoro-3-methyl-2-(4-phenyl-1-indolinyl)quinoline-4-carboxylate
• CAS NO: 179473-54-2
• Molecular Weight: 412.463
• Mol File: 179473-54-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: methyl 6-fluoro-3-methyl-2-(4-phenyl-1-indolinyl)quinoline-4-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 6-fluoro-3-methyl-2-(4-phenyl-1-indolinyl)quinoline-4-carboxylate(179473-54-2)
• EPA Substance Registry System: methyl 6-fluoro-3-methyl-2-(4-phenyl-1-indolinyl)quinoline-4-carboxylate(179473-54-2)

Safety Data

• Hazardous Substances Data: 179473-54-2(Hazardous Substances Data)

Upstream product

• 98-80-6 phenylboronic acid 
• 170568-85-1 6-fluoro-2-oxo-1,2-dihydro-quinoline-4-carboxylic acid 
• 107622-50-4 2-nitro-6-phenyltoluene 
• 55289-35-5 2-bromo-6-nitrotoluene 
• 35577-92-5 4-phenyl-1H-indole 
• 179473-53-1 4-phenyl-2,3-dihydro-1H-indole 
• 179473-51-9 methyl 2-bromo-6-fluoro-3-methylquinoline-4-carboxylate 
• 179473-50-8 4-carbomethoxy-6-fluoro-3-methylquinolin-2-one 

Relevant articles and documents

Heteroatom- and carbon-linked biphenyl analogs of Brequinar as immunosuppressive agents

Structure-activity relationships were explored for some analogs of Brequinar having a linking atom between the 2-biphenyl substituent and the quinoline ring. Activities as inhibitors of dihydroorotate dehydrogenase and the mixed lymphocyte reaction were related to the overall shape and lipophilicity of the 2-substituent.