179618-59-8

Basic information

• Product Name: 5-[(3E,5E)-9-(4-Methoxy-benzyloxy)-3-methyl-nona-3,5-dienyl]-2,2,4,4-tetramethyl-[1,3]dioxolane
• Synonyms: 5-[(3E,5E)-9-(4-Methoxy-benzyloxy)-3-methyl-nona-3,5-dienyl]-2,2,4,4-tetramethyl-[1,3]dioxolane
• CAS NO: 179618-59-8
• Molecular Weight: 402.574
• Mol File: 179618-59-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 5-[(3E,5E)-9-(4-Methoxy-benzyloxy)-3-methyl-nona-3,5-dienyl]-2,2,4,4-tetramethyl-[1,3]dioxolane(CAS DataBase Reference)
• NIST Chemistry Reference: 5-[(3E,5E)-9-(4-Methoxy-benzyloxy)-3-methyl-nona-3,5-dienyl]-2,2,4,4-tetramethyl-[1,3]dioxolane(179618-59-8)
• EPA Substance Registry System: 5-[(3E,5E)-9-(4-Methoxy-benzyloxy)-3-methyl-nona-3,5-dienyl]-2,2,4,4-tetramethyl-[1,3]dioxolane(179618-59-8)

Safety Data

• Hazardous Substances Data: 179618-59-8(Hazardous Substances Data)

Upstream product

• 40036-54-2 (E)-5-(3,3-dimethyloxiran-2-yl)-3-methylpent-2-en-1-ol 
• 119649-45-5 4-(p-methoxybenzyloxy)butan-1-ol 
• 824-94-2 p-methoxybenzyl chloride 
• 83324-69-0 (E)-8-bromo-2,3-O-isopropylidene-2,6-dimethyl-6-octene-2,3-diol 
• 124150-94-3 (E)-3-methyl-5-(2,2,5,5-tetramethyl-1,3-dioxolan-4-yl)pent-2-en-1-ol 
• 106-24-1 Geraniol 
• 119649-27-3 4-((4-methoxybenzyl)oxy)butanal 
• 179618-58-7 [(E)-3-Methyl-5-(2,2,5,5-tetramethyl-[1,3]dioxolan-4-yl)-pent-2-enyl]-phosphonic acid diethyl ester 

Downstream Products

• 179618-64-5 (4E,6E,10R)-10-methoxy-1-(4-methoxybenzyl)oxy-7-methyltrideca-4,6,12-triene 
• 179618-63-4 (4E,6E,10R)-10-hydroxy-1-(4-methoxybenzyl)oxy-7-methyltrideca-4,6,12-triene 
• 179618-62-3 (4E,6E)-10-(4-Methoxy-benzyloxy)-4-methyl-deca-4,6-dienal 
• 155233-30-0 curacin A 
• 179618-61-2 (6E,8E)-12-(4-Methoxy-benzyloxy)-2,6-dimethyl-dodeca-6,8-diene-2,3-diol 

Relevant articles and documents

Asymmetric total synthesis of curacin A

Curacin A (1), a novel antimitotic agent, was synthesized in a highly stereo-controlled manner. The key steps were (1) an asymmetric allylation using a chiral allyltitanium reagent and a double-asymmetric Simmons-Smith cyclopropanation to introduce three chiral centers, (2) Wittig and Wittig- Horner reactions to construct the C(3-4) and C(7-10) alkenes, and (3) a direct conversion of the thiazolidine to the thiazoline.