17972-12-2

Basic information

• Product Name: 4-methoxybenzylideneethylamine
• Synonyms: 4-methoxybenzylideneethylamine
• CAS NO: 17972-12-2
• Molecular Weight: 163.219
• Mol File: 17972-12-2.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 4-methoxybenzylideneethylamine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-methoxybenzylideneethylamine(17972-12-2)
• EPA Substance Registry System: 4-methoxybenzylideneethylamine(17972-12-2)

Safety Data

• Hazardous Substances Data: 17972-12-2(Hazardous Substances Data)

Upstream product

• 110079-25-9 C₁₀H₁₄ClNO 
• 123-11-5 4-methoxy-benzaldehyde 
• 75-04-7 ethylamine 

Downstream Products

• 849922-78-7 C₂₀H₁₇NO₄ 
• 1627130-75-9 4-(3-chloro-4,5-dimethoxyphenyl)-5-(4-methoxyphenyl)-1-ethylimidazole 
• 1627130-76-0 4-(3-bromo-4,5-dimethoxyphenyl)-5-(4-methoxyphenyl)-1-ethylimidazole 

Relevant articles and documents

Synthesis of fluorinated pyrimidinones

A method for the construction of fluorinated pyrimidinones based on the reaction of cyanodifluoromethyl- substituted amines with isocyanates is described. The use of ortho-iodophenylisocyanate in this reaction followed by copper catalyzed intramolecular amination affords fluorinated fused heterocycles - 4-fluoropyrimido[1,6-a]benzimidazol-1(2H)-ones.

Synthesis of 2-alkyl-1-aryl-1,2-dihydrochromeno[2,3-c]pyrrole-3,9-dione derivatives

A preparative procedure for the synthesis of 2-alkyl-1-aryl-1,2- dihydrochromeno[2,3-c]pyrrole-3,9-diones from methyl 4-(o-hydroxyphenyl)-2,4- dioxobutanoate, aromatic aldehyde, and aliphatic amine is described.

Reactions of N-Chloro-N-alkylbenzylamines with Amines in Acetonitrile. Origin of Steric Effect in Imine-Forming Elimination

Reaction of N-chloro-N-alkylbenzylamines in which the alkyl group is Me, Et, i-Pr, sec-Bu, and t-Bu with MeNH2 and Et2NH in MeCN have been studied kinetically.The eliminations are quantitative and regiospecific, producing only N-benzylidenealkylamines.The relative rates of elimination for Me/Et/i-Pr/sec-Bu/t-Bu alkyl substituents are 1/0.6/0.4/0.3/0.1 with MeNH2 and 1/0.5/0.3/0.2/0.03 with Et2NH, respectively.Comparison with published data reveals that Charton's value for the imine-forming elimination decreases with the variation of the base-solvent from MeONa-MeOH to MeNH2-MeCN but increases when the base is changed from MeNH2 to Et2NH.For a given base, Hammett ρ and kH/kD values decrease and the ΔH(excit.) and ΔS(excit.) values increase with bulkier alkyl substituents.From these results, the origin of the steric effect in imine-forming elimination is attributed to the repulsive interaction between the alkyl group and the base in the transition state.