179866-74-1 Usage
Description
(R)-(+)-6,6'-DIBROMO-2,2'-BIS(METHOXYMETHOXY)-1,1'-BINAPHTHYL is a chiral compound characterized by its binaphthyl core structure, with bromo substituents at the 6,6' positions and methoxymethoxy groups at the 2,2' positions. This molecule is known for its unique stereochemistry and is widely utilized in various chemical and pharmaceutical applications due to its versatile functional groups and structural features.
Uses
Used in Chemical Synthesis:
(R)-(+)-6,6'-DIBROMO-2,2'-BIS(METHOXYMETHOXY)-1,1'-BINAPHTHYL is used as an intermediate in the symmetric synthesis of BINOL-terpyridine ligands. These ligands are essential in the development of novel catalysts and coordination complexes, which find applications in various chemical reactions, including asymmetric catalysis and metal-organic frameworks.
Used in Pharmaceutical Industry:
(R)-(+)-6,6'-DIBROMO-2,2'-BIS(METHOXYMETHOXY)-1,1'-BINAPHTHYL serves as the starting material for the preparation of a variety of 6,6' and 3,3'-substituted BINOLS. These substituted BINOLS are valuable building blocks in the synthesis of pharmaceutical compounds, particularly those with chiral centers. They are used in the development of drugs targeting various therapeutic areas, such as central nervous system disorders, cardiovascular diseases, and oncology.
Check Digit Verification of cas no
The CAS Registry Mumber 179866-74-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,9,8,6 and 6 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 179866-74:
(8*1)+(7*7)+(6*9)+(5*8)+(4*6)+(3*6)+(2*7)+(1*4)=211
211 % 10 = 1
So 179866-74-1 is a valid CAS Registry Number.
179866-74-1Relevant articles and documents
A fluorinated binaphthyl chiral dopant for fluorinated liquid crystal blue phases
Kakisaka,Higuchi,Okumura,Kikuchi
, p. 6467 - 6470 (2014)
A 6,6′-fluorinated binaphthyl enantiomer, (R)-1, was applied as a chiral dopant to produce cholesteric blue phases (BPs). A fluorinated nematic liquid crystal doped with (R)-1 showed lower critical chirality to induce a BP and a larger temperature range of BPs than that doped with a conventional chiral dopant. This journal is the Partner Organisations 2014.
Synthesis, properties, and structures of functionalized peri -xanthenoxanthene
Lv, Na,Xie, Meilan,Gu, Weibing,Ruan, Huanyang,Qiu, Song,Zhou, Chunshan,Cui, Zheng
supporting information, p. 2382 - 2385 (2013/07/04)
Three types of alkylated peri-xanthenoxanthene (PXX) have been synthesized employing efficient synthetic routes. These heteroaromatic compounds exhibited different electronic and crystal structures according to UV-vis spectra, electrochemical measurements, and X-ray structural analyses. Among them, 1,7-DOPXX has been demonstrated as an active material for organic field-effect transistors with promising mobility and a high on/off ratio simultaneously.
Immobilization of asymmetric multifunctional catalysts on an insoluble polymer
Matsunaga,Ohshima,Shibasaki
, p. 8473 - 8478 (2007/10/03)
Polymer-supported linked-BINOL was synthesized to immobilize asymmetric catalysts with two BINOL units. The advantage of the polymer-supported linked-BINOL over randomly polymer-supported BINOL was confirmed by asymmetric Michael reaction. A novel polymer