179898-73-8

Basic information

• Product Name: 6-AMINO-3,3-DIMETHYL-2,3-DIHYDRO-INDOLE
• Synonyms: 6-AMINO-3,3-DIMETHYL-2,3-DIHYDRO-INDOLE;3,3-Dimethylindolin-6-amine;2,3-Dihydro-3,3-dimethyl-1H-indol-6-amine;6-Amino-3,3-dimethylindoline;3,3-dimethyl-1,2-dihydroindol-6-amine
• CAS NO: 179898-73-8
• Molecular Formula: C10H14N2
• Molecular Weight: 162.24
• Mol File: 179898-73-8.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 295.831 °C at 760 mmHg
• Flash Point: 154.421 °C
• Appearance: /
• Density: 1.044
• Vapor Pressure: 0.001mmHg at 25°C
• Refractive Index: 1.567
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 5.80±0.40(Predicted)
• CAS DataBase Reference: 6-AMINO-3,3-DIMETHYL-2,3-DIHYDRO-INDOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 6-AMINO-3,3-DIMETHYL-2,3-DIHYDRO-INDOLE(179898-73-8)
• EPA Substance Registry System: 6-AMINO-3,3-DIMETHYL-2,3-DIHYDRO-INDOLE(179898-73-8)

Safety Data

• Hazardous Substances Data: 179898-73-8(Hazardous Substances Data)

Usage

General Description

6-AMINO-3,3-DIMETHYL-2,3-DIHYDRO-INDOLE is a chemical compound with the molecular formula C11H14N2. It is a derivative of the indole compound and contains an amino group and two methyl groups. 6-AMINO-3,3-DIMETHYL-2,3-DIHYDRO-INDOLE is often used as a building block in organic synthesis and drug discovery research. It has also been studied for its potential biological activities, including anti-cancer and anti-microbial properties. 6-AMINO-3,3-DIMETHYL-2,3-DIHYDRO-INDOLE is a versatile molecule with potential applications in pharmaceuticals, agrochemicals, and materials science.

InChI:InChI=1/C10H14N2/c1-10(2)6-12-9-5-7(11)3-4-8(9)10/h3-5,12H,6,11H2,1-2H3

Upstream product

• 179898-72-7 3,3-dimethyl-6-nitro-2,3-dihydro-1H-indole 
• 1914-02-9 3,3-dimethylindoline 
• 615-36-1 2-bromoaniline 
• 207122-91-6 (2-Bromo-phenyl)-(2-methyl-allyl)-amine 

Relevant articles and documents

New nonsteroidal androgen receptor modulators based on 4-(trifluoromethyl)-2(1H)-pyrrolidino[3,2-g]quinolinone

A series of 2(1H)-pyrrolidino[3,2-g]quinolinones was prepared and tested for the ability to modulate the transcriptional activity of the human androgen receptor (hAR). The parent compound, 4-(trifluoromethyl)-2(1H)-pyrrolidino[3,2-g]quinolinone, displayed moderate interaction with hAR, but more substituted analogues, particularly 6,7-disubstituted compounds, were potent hAR agonists in vitro.

STEROID RECEPTOR MODULATOR COMPOUNDS AND METHODS

Non-steroidal compounds which are high affinity, high selectivity modulators for steroid receptors are disclosed. Also disclosed are pharmaceutical compositions incorporating such compounds, methods for employing the disclosed compounds and compositions for treating patients requiring steroid receptor agonist or antagonist therapy, intermediates useful in the preparation of the compounds and processes for the preparation of the steroid receptor modulator compounds.

STEROID RECEPTOR MODULATOR COMPOUNDS AND METHODS

Non-steroidal compounds which are high affinity, high selectivity modulators for steroid receptors are disclosed. Also disclosed are pharmaceutical compositions incorporating such compounds, methods for employing the disclosed compounds and compositions for treating patients requiring steroid receptor agonist or antagonist therapy, intermediates useful in the preparation of the compounds and processes for the preparation of the steroid receptor modulator compounds.