17990-20-4Relevant articles and documents
Microbial Transformation of cis-Abienol
Hieda, Tadaharu,Mikami, Yoichi,Obi, Yukiteru,Kisaki, Takuro
, p. 2249 - 2256 (2007/10/02)
A study was made of the microbial transformation of cis-abienol, a main precursor of the tobacco aroma principle, by an unidentified soil bacterium JTS-162.Four new compounds were isolated from the culture broth as transformation products.They were elucidated to be (12Z)-labda-8(17),12,14-triene, (12Z)-labda-8(17),12,14-trien-18-ol, (12Z)-labda-8(17),12,14-trien-18-al and 4,18,19-tri-nor-3,4-seco-5-oxo-(12Z)-labda-8(17),12,14-trien-3-oic acid by spectrometry and syntheses.Based on experiments with a degradation sequence, the biotransformation pathway of cis-abienol by the bacterium was proposed.