179949-73-6

Basic information

• Product Name: 4-(tert-Butyl-dimethyl-silanyloxy)-2-iodo-cyclohex-2-enone
• Synonyms: 4-(tert-Butyl-dimethyl-silanyloxy)-2-iodo-cyclohex-2-enone
• CAS NO: 179949-73-6
• Molecular Weight: 352.288
• Mol File: 179949-73-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-(tert-Butyl-dimethyl-silanyloxy)-2-iodo-cyclohex-2-enone(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(tert-Butyl-dimethyl-silanyloxy)-2-iodo-cyclohex-2-enone(179949-73-6)
• EPA Substance Registry System: 4-(tert-Butyl-dimethyl-silanyloxy)-2-iodo-cyclohex-2-enone(179949-73-6)

Safety Data

• Hazardous Substances Data: 179949-73-6(Hazardous Substances Data)

Upstream product

• 119414-47-0 (+/-)-4-(tert-butyl(dimethyl)silyloxy)-2-cyclohexen-1-one 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 30182-12-8 4-hydroxy-2-cyclohexenone 

Downstream Products

• 93752-54-6 LL-C10037α 
• 1560848-62-5 (1S,5S,6R)-5-[(tert-butyldimethylsilyl)oxy]-7-[(1R)-1-(4-methoxyphenyl)ethyl]-7-azabicyclo[4.1.0]hept-3-en-2-one 
• 1560848-65-8 (1S,3R,5S,6R,7R)-6-[(tert-butyldimethylsilyl)oxy]-8-[(1R)-1-(4-methoxyphenyl)ethyl]-4-oxa-8-azatricyclo[5.1.0.0^3,5]octan-2-one 
• 1560848-66-9 (1S,3S,5R,6R,7R)-6-[(tert-butyldimethylsilyl)oxy]-8-[(1R)-1-(4-methoxyphenyl)ethyl]-4-oxa-8-azatricyclo-[5.1.0.03,5]octan-2-one 
• 1560848-51-2 (1R,5R,6S)-5-[(tert-butyldimethylsilyl)oxy]-7-[(1R)-1-(4-methoxyphenyl)ethyl]-7-azabicyclo[4.1.0]hept-3-en-2-one 
• 1560848-54-5 (1R,3S,5R,6S,7S)-6-[(tert-butyldimethylsilyl)oxy]-8-[(1R)-1-(4-methoxyphenyl)ethyl]-4-oxa-8-azatricyclo[5.1.0.0^3,5]octan-2-one 
• 1560848-56-7 (1R,3R,5S,6S,7S)-6-[(tert-butyldimethylsilyl)oxy]-8-[(1R)-1-(4-methoxyphenyl)ethyl]-4-oxa-8-azatricyclo-[5.1.0.0^3,5]octan-2-one 
• 1560848-42-1 (1R,5R,6S)-5-[(tert-butyldimethylsilyl)oxy]-7-[(1R)-1-(4-methoxyphenyl)ethyl]-7-azabicyclo[4.1.0]heptan-2-one 
• 1560848-45-4 (1S,5S,6R)-5-[(tert-butyldimethylsilyl)oxy]-7-[(1R)-1-(4-methoxyphenyl)ethyl]-7-azabicyclo[4.1.0]heptan-2-one 
• 1560848-48-7 (1S,5R,6R)-5-[(tert-butyldimethylsilyl)oxy]-7-[(1R)-1-(4-methoxyphenyl)ethyl]-7-azabicyclo[4.1.0]heptan-2-one 
• 1560848-50-1 (1R,5S,6S)-5-[(tert-butyldimethylsilyl)oxy]-7-[(1R)-1-(4-methoxyphenyl)ethyl]-7-azabicyclo[4.1.0]heptan-2-one 
• 179949-79-2 4-(tert-Butyl-dimethyl-silanyloxy)-2-[(E)-1-(tert-butyl-dimethyl-silanyloxymethyl)-buta-1,3-dienyl]-cyclohex-2-enone 
• 1026185-26-1 3-(tert-Butyl-dimethyl-silanyloxy)-1-iodo-6-trimethylsilanyloxy-cyclohexene 
• 161407-87-0 4-Hydroxy-2-((E)-1-hydroxymethyl-buta-1,3-dienyl)-cyclohex-2-enone 

Relevant articles and documents

A selective procedure for α-alkenylation of enones involving Pd-catalyzed alkenyl-alkenyl coupling and its application to a convergent and efficient synthesis of nakienone B

A convergent and efficient synthesis of a marine natural product, nakienone B (1), was achieved using a new protocol for α-alkenylation of enones involving Pd-catalyzed coupling of alkenylzincs with alkenyl iodides. This protocol features (i) avoidance of acidic conditions and (ii) flexibility in charge affinity pattern with respect to the two alkenyl groups to be coupled.