180064-38-4

Basic information

• Product Name: PHOSPHONIC ACID, (1-HYDROXY-2-IMIDAZO(1,2-A)PYRIDIN-3-YLETHYLIDENE)BIS-
• Synonyms: PHOSPHONIC ACID, (1-HYDROXY-2-IMIDAZO(1,2-A)PYRIDIN-3-YLETHYLIDENE)BIS-;1-Hydroxy-2-(imidazo[1,2-a]pyridin-3-yl)ethane-1,1-bis(phosphonic acid);Minodronic acid;(1-Hydroxy-2-imidazo[1,2-A]pyridin-3-yl-1-ethyl)-1,1-bisphos phonate;Nsc725590;Bonoteo;BPH 261;ONO 5920
• CAS NO: 180064-38-4
• Molecular Formula: C9H12N2O7P2
• Molecular Weight: 322.148302
• EINECS: 1592732-453-0
• Mol File: 180064-38-4.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Density: 1.973 g/cm³
• Refractive Index: 1.744
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 1.48±0.10(Predicted)
• CAS DataBase Reference: PHOSPHONIC ACID, (1-HYDROXY-2-IMIDAZO(1,2-A)PYRIDIN-3-YLETHYLIDENE)BIS-(CAS DataBase Reference)
• NIST Chemistry Reference: PHOSPHONIC ACID, (1-HYDROXY-2-IMIDAZO(1,2-A)PYRIDIN-3-YLETHYLIDENE)BIS-(180064-38-4)
• EPA Substance Registry System: PHOSPHONIC ACID, (1-HYDROXY-2-IMIDAZO(1,2-A)PYRIDIN-3-YLETHYLIDENE)BIS-(180064-38-4)

Safety Data

• Hazardous Substances Data: 180064-38-4(Hazardous Substances Data)

Usage

Description

PHOSPHONIC ACID, (1-HYDROXY-2-IMIDAZO(1,2-A)PYRIDIN-3-YLETHYLIDENE)BISis a complex organic compound with a unique structure that features a bis-phosphonic acid group connected to two imidazo[1,2-a]pyridine moieties. PHOSPHONIC ACID, (1-HYDROXY-2-IMIDAZO(1,2-A)PYRIDIN-3-YLETHYLIDENE)BISis characterized by its ability to form strong coordination bonds with metal ions, making it a promising candidate for various applications in different industries.

Uses

Used in Pharmaceutical Industry:
PHOSPHONIC ACID, (1-HYDROXY-2-IMIDAZO(1,2-A)PYRIDIN-3-YLETHYLIDENE)BISis used as a pharmaceutical agent for the treatment of osteoporosis. It is a third-generation bisphosphonate, similar to Minodronic acid, which inhibits the activity of recombinant human FPP synthase, playing a crucial role in bone metabolism. PHOSPHONIC ACID, (1-HYDROXY-2-IMIDAZO(1,2-A)PYRIDIN-3-YLETHYLIDENE)BIShelps increase bone mass and improve bone strength, reducing the risk of fractures in patients with osteoporosis.
Used in Chemical Synthesis:
In the field of chemical synthesis, PHOSPHONIC ACID, (1-HYDROXY-2-IMIDAZO(1,2-A)PYRIDIN-3-YLETHYLIDENE)BIScan be used as a building block or intermediate for the development of new compounds with potential applications in various industries. Its unique structure and strong metal-chelating properties make it a valuable component in the synthesis of coordination complexes, catalysts, and other specialty chemicals.
Used in Environmental Applications:
PHOSPHONIC ACID, (1-HYDROXY-2-IMIDAZO(1,2-A)PYRIDIN-3-YLETHYLIDENE)BIScan be employed in environmental applications, such as water treatment and soil remediation, due to its ability to form stable complexes with metal ions. This property allows it to effectively remove heavy metals and other contaminants from water and soil, contributing to a cleaner and safer environment.
Used in Material Science:
In the field of material science, PHOSPHONIC ACID, (1-HYDROXY-2-IMIDAZO(1,2-A)PYRIDIN-3-YLETHYLIDENE)BIScan be utilized in the development of advanced materials with specific properties. Its strong coordination capabilities can be harnessed to create new materials with improved mechanical, thermal, or electrical properties, finding applications in various industries such as aerospace, electronics, and automotive.

Originator

Astellas Pharma (Japan)

InChI:InChI=1/C9H12N2O7P2/c12-9(19(13,14)15,20(16,17)18)5-7-6-10-8-3-1-2-4-11(7)8/h1-4,6,12H,5H2,(H2,13,14,15)(H2,16,17,18)