18009-12-6

Basic information

• Product Name: 4(1H)-Quinazolinone, 6-bromo-3-(4-chlorophenyl)-2,3-dihydro-2-thioxo-
• CAS NO: 18009-12-6
• Molecular Formula: C14H8BrClN2OS
• Molecular Weight: 367.653
• Mol File: 18009-12-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4(1H)-Quinazolinone, 6-bromo-3-(4-chlorophenyl)-2,3-dihydro-2-thioxo-(CAS DataBase Reference)
• NIST Chemistry Reference: 4(1H)-Quinazolinone, 6-bromo-3-(4-chlorophenyl)-2,3-dihydro-2-thioxo-(18009-12-6)
• EPA Substance Registry System: 4(1H)-Quinazolinone, 6-bromo-3-(4-chlorophenyl)-2,3-dihydro-2-thioxo-(18009-12-6)

Safety Data

• Hazardous Substances Data: 18009-12-6(Hazardous Substances Data)

Upstream product

• 75-15-0 carbon disulfide 
• 106-47-8 4-chloro-aniline 
• 5794-88-7 5-Bromo-2-aminobenzoic acid 

Downstream Products

• 95353-82-5 3-Amino-6-bromo-2-(4-chloro-phenylamino)-3H-quinazolin-4-one 
• 115808-64-5 6-Bromo-3-(4-chloro-phenyl)-2-hydrazino-3H-quinazolin-4-one 

Relevant articles and documents

Synthesis and reactions of some 3-aryl-2-thioxoquinazolin-4(3H)-ones

A series of 3-aryl-2-thioxoquinazolin-4(3H)-ones la-g are prepared in good yields from reactions of anthranilic acids, aromatic amines and carbon disulfide under basic conditions in one step. Reaction of aminophenyl derivatives la,b with D-glucose affords the corresponding N-glucosylamines 4a,b in very good yields. Diazotization of la,b followed by reactions with aromatic amines yield the corresponding azo dyes 6a-f in 40-56% yields. The fastness for 6 has been studied. Compounds 6a,b,f have been proved to biologically active.