1801-99-6

Basic information

• Product Name: Methanone, (2-mercaptophenyl)phenyl-
• CAS NO: 1801-99-6
• Molecular Formula: C13H10OS
• Molecular Weight: 214.288
• Mol File: 1801-99-6.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: Methanone, (2-mercaptophenyl)phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Methanone, (2-mercaptophenyl)phenyl-(1801-99-6)
• EPA Substance Registry System: Methanone, (2-mercaptophenyl)phenyl-(1801-99-6)

Safety Data

• Hazardous Substances Data: 1801-99-6(Hazardous Substances Data)

Upstream product

• 7283-41-2 thiosalicilyc acid 
• 591-51-5 phenyllithium 
• 147-93-3 Thiosalicylic acid 
• 1237533-86-6 S-(2-benzoylphenyl) dimethylcarbamothioate 
• 108-95-2 phenol 
• 98-88-4 benzoyl chloride 
• 117-99-7 2-Hydroxybenzophenone 
• 131117-88-9 O-(2-benzoylphenyl) dimethylthiocarbamate 
• 108-98-5 thiophenol 
• 100-47-0 benzonitrile 

Downstream Products

• 1237533-86-6 S-(2-benzoylphenyl) dimethylcarbamothioate 
• 106225-37-0 2-(4-methoxyphenyl)-3-phenylbenzo[b]thiophene 

Relevant articles and documents

Substituted Benzothietes: Synthesis and a Quantum Chemical Investigation of Their Cycloreversion Properties

A flexible synthesis for highly substituted benzothietes that does not require flash-vacuum pyrolysis was developed. This allows for the use of a number of functional groups and nonvaporizable molecules. Highly stabilized derivatives were isolated. The molecular orbital properties of various benzothietes were evaluated by density functional methods. The mechanism of the cycloreversion of the four-membered ring was compared to that of the oxygen-containing analogues.

Enantioselective Synthesis of Indolines, Benzodihydrothiophenes, and Indanes by C?H Insertion of Donor/Donor Carbenes

We employ a single catalyst/oxidant system to enable the asymmetric syntheses of indolines, benzodihydrothiophenes, and indanes by C?H insertion of donor/donor carbenes. This methodology enables the rapid construction of densely substituted five-membered rings that form the core of many drug targets and natural products. Furthermore, oxidation of hydrazones to the corresponding diazo compounds proceeds in situ, enabling a relatively facile one- or two-pot protocol in which isolation of potentially explosive diazo alkanes is avoided. Regioselectivity studies were performed to determine the impact of sterics and electronics in donor/donor metal carbene C?H insertions to form indolines. This methodology was applied to a variety of substrates in high yield, diastereomeric, and enantiomeric ratios and to the synthesis of a patented indane estrogen receptor agonist with anti-cancer activity.

ALDEHYDE CAPTURE LIGATION TECHNOLOGY FOR SYNTHESIS OF AMIDE BONDS

The present invention relates to ligation agents and their use in making an amide ligation product. Methods of making the ligation agents are also disclosed.