1801747-11-4 Usage
Description
SHP099 (hydrochloride) is a chemical compound that serves as a reagent in the preparation of substituted piperidinylpyrazinamines and analogs. These compounds are known to inhibit the activity of SHP2, a protein that plays a crucial role in various cellular processes. By targeting SHP2, SHP099 (hydrochloride) and its derivatives have the potential to be used in the treatment of various diseases.
Uses
Used in Pharmaceutical Industry:
SHP099 (hydrochloride) is used as a reagent for the synthesis of substituted piperidinylpyrazinamines and analogs, which are important for inhibiting the activity of SHP2. This inhibition can be beneficial in treating diseases where SHP2 plays a significant role in their progression.
Used in Research and Development:
In the field of research and development, SHP099 (hydrochloride) is utilized to create novel compounds that can potentially be used as therapeutic agents. By understanding the interactions between these compounds and SHP2, researchers can gain insights into the underlying mechanisms of various diseases and develop targeted treatments.
Used in Drug Discovery:
SHP099 (hydrochloride) plays a vital role in drug discovery, as it helps in the development of new drugs that can target SHP2. By inhibiting the activity of this protein, these drugs may offer effective treatment options for patients suffering from diseases associated with SHP2 dysregulation.
Check Digit Verification of cas no
The CAS Registry Mumber 1801747-11-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,8,0,1,7,4 and 7 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1801747-11:
(9*1)+(8*8)+(7*0)+(6*1)+(5*7)+(4*4)+(3*7)+(2*1)+(1*1)=154
154 % 10 = 4
So 1801747-11-4 is a valid CAS Registry Number.
1801747-11-4Relevant articles and documents
1 -PYRIDAZIN-/TRIAZIN-3-YL-PIPER(-AZINE)/IDINE/PYROLIDINE DERIVATIVES AND AND COMPOSITIONS THEREOF FOR INHIBITING THE ACTIVITY OF SHP2
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Paragraph 00274, (2015/08/03)
The present invention relates to compounds of formula (I): in which m, p,Y1 Y2, Y3, R1, R2a, R2b, R3a, R3b, R4a, R4b, R4a and R5b are defined in the claims; capable of inhibiting the activity of SHP2. The invention further provides a process for the preparation of compounds of the invention, pharmaceutical preparations comprising such compounds and methods of using such compounds and compositions in the management of diseases or disorders associated with the aberrant activity of SHP2.
