180253-72-9

Basic information

• Product Name: (2,6-dichloro-4-nitrophenyl)(phenyl)sulfane
• Synonyms: (2,6-dichloro-4-nitrophenyl)(phenyl)sulfane
• CAS NO: 180253-72-9
• Molecular Weight: 300.165
• Mol File: 180253-72-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (2,6-dichloro-4-nitrophenyl)(phenyl)sulfane(CAS DataBase Reference)
• NIST Chemistry Reference: (2,6-dichloro-4-nitrophenyl)(phenyl)sulfane(180253-72-9)
• EPA Substance Registry System: (2,6-dichloro-4-nitrophenyl)(phenyl)sulfane(180253-72-9)

Safety Data

• Hazardous Substances Data: 180253-72-9(Hazardous Substances Data)

Upstream product

• 3107-19-5 3,5-dichloro-4-fluoro-nitrobenzene 
• 108-98-5 thiophenol 
• 20098-48-0 3,4,5-trichloronitrobenzen 
• 930-69-8 sodium thiophenolate 
• 98137-94-1 1-bromo-2,6-dichloro-4-nitrobenzene 

Downstream Products

• 1620782-56-0 N³-(4-benzenesulfonyl-3,5-dichlorophenyl)-1H-[1,2,4]triazole-3,5-diamine 
• 1620782-55-9 N³-(4-benzenesulfinyl-3,5-dichlorophenyl)-1H-[1,2,4]triazole-3,5-diamine 
• 1620878-53-6 (Z)-methyl N'-cyano-N-(3,5-dichloro-4-(phenylthio)phenyl)carbamimidothioate 
• 1620782-81-1 1,3-dichloro-5-isothiocyanato-2-phenylsulfanylbenzene 
• 1620782-54-8 N³-(3,5-dichloro-4-phenylsulfanylphenyl)-1H-[1,2,4]triazole-3,5-diamine 

Relevant articles and documents

ANTIVIRAL TRIAZOLE DERIVATIVES

The present invention discloses compounds of Formula I: wherein the variables in Formula I are defined as described herein. Also disclosed are pharmaceutical compositions containing such compounds and methods for using the compounds of Formula I in the prevention or treatment of HCV infection.

Reductively activated polar" nucleophilic aromatic substitution. IV [1]. Thermal and photochemical behavior of polychloro and polyfluoro-nitrobenzenes in front of soft nucleophiles

The nucleophilic aromatic substitution of pentachloronitrobenzene (PCNB) with benzenethiolate and benzeneselenide anions in aqueous solution give rise to fast nitro group substitution in both cases. In the same conditions, pentafluoronitrobenzene (PFNB) and 3,4,5-trichloronitrobenzene (TCNB) undergo substitution of the halogen atom placed in para position with respect to the nitro group. Mechanistic studies suggest that the reactions of PCNB and PFNB (substitution of very electronegative leaving groups) follow a mechanism that includes a "polar" attack of the nucleophile on the aromatic substrate in the first step and a fast "radical" evolution of the o-complex intermediate. On the other hand, the chloride substitution in the TCNB reactions follows the classical SNAr mechanism. The photochemical reactions of PCNB, PFNB and TCNB in the presence of nucleophiles (electron donors) lead in all cases to photoreduction products (anilines) probably through the aromatic radical anion. Springer-Verlag 1996.