180403-02-5

Basic information

• Product Name: 2-butyl-4-methyl-2,3,4,5-tetrahydro-1,4-benzoxazepine-3,5-dione
• CAS NO: 180403-02-5
• Molecular Weight: 247.294
• Mol File: 180403-02-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-butyl-4-methyl-2,3,4,5-tetrahydro-1,4-benzoxazepine-3,5-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 2-butyl-4-methyl-2,3,4,5-tetrahydro-1,4-benzoxazepine-3,5-dione(180403-02-5)
• EPA Substance Registry System: 2-butyl-4-methyl-2,3,4,5-tetrahydro-1,4-benzoxazepine-3,5-dione(180403-02-5)

Safety Data

• Hazardous Substances Data: 180403-02-5(Hazardous Substances Data)

Upstream product

• 1862-88-0 N-methylsalicylamide 
• 5445-19-2 methyl 2-bromohexanoate 

Relevant articles and documents

Synthesis and properties of new 2-alkyl-1,4-benzoxazepine derivatives. Part I. Synthesis and cyclization of 2-phenoxyalkanoic acid derivatives

2-Alkyl-1,4-benzoxazepin-3,5-diones (8) were readily prepared by cyclodehydration of 2-(o-carbamoilphenoxy)alkanoic acids (7) in acetic anhydride, and with low yields by the same reaction of 2-(o-carboxyphenoxy)alkanoic acid amides (4). The novel acid amides 4 were synthesized from salicylaldehyde and 2-bromo esters 1, via formyl amides 3. The acid amides 7 were formed directly by condensation of salicylamides with 2-bromo esters 1 in dimethyl formamide or by hydrolysis of esters 6 obtained by the same reaction in methyl-ethyl ketone solution.