180596-44-5

Basic information

• Product Name: 7-(3-dimethylaminopropoxymethyl)-6,8-difluoro-2-(3-fluoro-4-pivaloylaminophenyl)-5-pivaloylamino-4H-1-benzopyran-4-one
• CAS NO: 180596-44-5
• Molecular Weight: 589.655
• Mol File: 180596-44-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 7-(3-dimethylaminopropoxymethyl)-6,8-difluoro-2-(3-fluoro-4-pivaloylaminophenyl)-5-pivaloylamino-4H-1-benzopyran-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 7-(3-dimethylaminopropoxymethyl)-6,8-difluoro-2-(3-fluoro-4-pivaloylaminophenyl)-5-pivaloylamino-4H-1-benzopyran-4-one(180596-44-5)
• EPA Substance Registry System: 7-(3-dimethylaminopropoxymethyl)-6,8-difluoro-2-(3-fluoro-4-pivaloylaminophenyl)-5-pivaloylamino-4H-1-benzopyran-4-one(180596-44-5)

Safety Data

• Hazardous Substances Data: 180596-44-5(Hazardous Substances Data)

Upstream product

• 3179-63-3 3-Dimethylamino-1-propanol 
• 165180-39-2 6,8-difluoro-2-(3-fluoro-4-pivaloylaminophenyl)-7-methanesulfonyloxymethyl-5-pivaloylamino-4H-1-benzopyran-4-one 
• 165180-38-1 6,8-difluoro-2-(3-fluoro-4-pivaloylaminophenyl)-7-hydroxymethyl-5-pivaloylamino-4H-1-benzopyran-4-one 
• 165180-37-0 ethyl 4-tert-butyldimethylsilyloxymethyl-3,5-difluoro-6-pivaloylamino-2-(2-tetrahydropyranyloxy)benzoate 
• 165180-35-8 ethyl 3,5-difluoro-4-formyl-6-pivaloylamino-2-(2-tetrahydropyranyloxy) benzoate 
• 165180-36-9 ethyl 3,5-difluoro-4-hydroxymethyl-6-pivaloylamino-2-(2-tetrahydropyranyloxy) benzoate 
• 152835-84-2 ethyl 3,5-difluoro-6-pivaloylamino-2-(2-tetrahydropyranyloxy)-4-trimethylsilylbenzoate 
• 152835-78-4 ethyl 3,5-difluoro-6-(N-pivaloylamino)-2-(2-tetrahydropyranyloxy)benzoate 

Relevant articles and documents

Structure-activity relationships of the 7-substituents of 5,4-'diamino- 6,8,3'-trifluoroflavone, a potent antitumor agent

Recently, we reported that 5,4'-diamino-6,8,3'-trifluoroflavone (1b) exhibits potent antitumor activity against certain types of human cancer cell lines both in vitro and in vivo. Since the antiproliferative activity of 5,4'-diaminoflavon (1a), the lead c