18065-78-6 Usage
Description
1-(2-phenylethyl)pyridin-2(1H)-one, also known as 2-phenethyl-2-pyridone, is a chemical compound with the molecular formula C16H15NO. It is a derivative of pyridin-2(1H)-one and is commonly used in pharmaceutical research. 1-(2-phenylethyl)pyridin-2(1H)-one has been investigated for its potential as a drug candidate due to its anti-inflammatory and anti-cancer properties, as well as its ability to inhibit certain enzymes involved in disease processes. Research on 1-(2-phenylethyl)pyridin-2(1H)-one is ongoing, and it has shown promise as a potential therapeutic agent in various medical applications.
Uses
Used in Pharmaceutical Research:
1-(2-phenylethyl)pyridin-2(1H)-one is used as a research compound for its potential anti-inflammatory and anti-cancer properties. It is being investigated for its ability to inhibit certain enzymes involved in disease processes, which could lead to the development of new therapeutic agents for various medical conditions.
Used in Drug Development:
In the pharmaceutical industry, 1-(2-phenylethyl)pyridin-2(1H)-one is used as a potential drug candidate. Its study is focused on understanding its mechanisms of action and evaluating its efficacy and safety in treating specific diseases. 1-(2-phenylethyl)pyridin-2(1H)-one's potential applications in drug development are being explored to bring forth novel treatments for patients in need.
Used in Enzyme Inhibition Studies:
1-(2-phenylethyl)pyridin-2(1H)-one is also used as a tool in enzyme inhibition studies. Its ability to inhibit certain enzymes makes it a valuable compound for understanding the roles these enzymes play in disease processes and for developing targeted therapies that can disrupt these processes.
Overall, 1-(2-phenylethyl)pyridin-2(1H)-one is a versatile compound with potential applications in various areas of pharmaceutical research and development, making it an important compound for ongoing scientific investigation.
Check Digit Verification of cas no
The CAS Registry Mumber 18065-78-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,0,6 and 5 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 18065-78:
(7*1)+(6*8)+(5*0)+(4*6)+(3*5)+(2*7)+(1*8)=116
116 % 10 = 6
So 18065-78-6 is a valid CAS Registry Number.
18065-78-6Relevant articles and documents
Catalytic O- to N-Alkyl Migratory Rearrangement: Transition Metal-Free Direct and Tandem Routes to N-Alkylated Pyridones and Benzothiazolones
Mishra, Abhishek Kumar,Morgon, Nelson Henrique,Sanyal, Suparna,Robinson de Souza, Aguinaldo,Biswas, Srijit
, p. 3930 - 3939 (2018/09/14)
The present study reports the synthesis of N-alkylated pyridones and benzothiazolones via O- to N-alkyl group migration under transition metal-free TfOH-catalyzed reaction conditions for the first time, to the best of our knowledge. Primary as well as secondary alkyl groups smoothly migrate under the present reaction conditions. Moreover, a minor modification of the protocol used in this study is found to be applicable for an entirely new tandem synthesis of 2-alkoxy-N-heterocycles from the simplest starting materials in a solvent-free reaction conditions. Density Functional Theory (DFT) calculation identifies the energy species associated with the rearrangement, whereas, mechanistic experiments explore the role of the catalyst as the alkyl group transfer mediator. (Figure presented.).
Iron-catalyzed regioselective direct arylation at the C-3 position of N-alkyl-2-pyridone
Modak, Atanu,Rana, Sujoy,Maiti, Debabrata
, p. 296 - 303 (2016/09/09)
A number of pharmaceutical compounds possess an arylated 2-pyridone moiety. The existing reports using expensive starting materials and/or superstoichiometric metal salts have prompted us to explore a possible user-friendly method for their synthesis. In this report, we demonstrate an easy-to-handle reaction condition with an iron catalyst for the exclusive generation of C-3-arylated pyridone via C-H functionalization.
N- vs. O-alkylation in the Mitsunobu reaction of 2-pyridone
Comins, Daniel L.,Jianhua, Gao
, p. 2819 - 2822 (2007/10/02)
An N- vs. O-alkylation study of 2-pyridone with various alcohols and solvents under Mitsunobu conditions was carried out.
