1807-15-4 Usage
Description
17,21-dihydroxypregn-4-ene-3,20-dione 17,21-di(acetate) is a synthetic steroid derivative and an acetate ester of the hormone progesterone. It is a potent progestogen with a chemical structure that allows for better absorption and prolonged effects in the body.
Used in Hormone Therapy:
17,21-dihydroxypregn-4-ene-3,20-dione 17,21-di(acetate) is used as a hormone therapy agent for the treatment of various hormone-related conditions, such as menstrual disorders, endometriosis, and hormone replacement therapy. Its potent progestogenic activity helps regulate hormonal imbalances and alleviate symptoms associated with these conditions.
Used in Contraceptive Applications:
17,21-dihydroxypregn-4-ene-3,20-dione 17,21-di(acetate) is used as a contraceptive agent in combination with other hormones. Its progestogenic properties contribute to the prevention of ovulation, thereby reducing the chances of pregnancy.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 17,21-dihydroxypregn-4-ene-3,20-dione 17,21-di(acetate) is used as an active pharmaceutical ingredient in the development of hormone-related medications. Its acetate form enhances the drug's bioavailability and effectiveness, making it a valuable component in the formulation of various therapeutic products.
Check Digit Verification of cas no
The CAS Registry Mumber 1807-15-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,8,0 and 7 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1807-15:
(6*1)+(5*8)+(4*0)+(3*7)+(2*1)+(1*5)=74
74 % 10 = 4
So 1807-15-4 is a valid CAS Registry Number.
InChI:InChI=1/C25H34O6/c1-15(26)30-14-22(29)25(31-16(2)27)12-9-21-19-6-5-17-13-18(28)7-10-23(17,3)20(19)8-11-24(21,25)4/h13,19-21H,5-12,14H2,1-4H3/t19-,20+,21+,23+,24+,25+/m1/s1
1807-15-4Relevant articles and documents
TRANSFORMED STEROIDS. 186. USE OF THE DIACETOXYIODOBENZENE-IODINE SYSTEM FOR THE CONVERSION OF EPIMERIC 17-ETHYNYLANDROST-4-EN-17-OL-3-ONES TO PREGNANES
Turuta, A. M.,Vesela, I. V.,Kamernitskii, A. V.,Vlakhov, Rodoslav
, p. 2508 - 2511 (1991)
Epimeric 17-acetoxy-17-ethynylandrost-4-en-3-ones react with diacetoxyiodobenzene and iodine in acetic acid or methanol in an unusual manner to give 17-acetoxy-21,21-diiodo-17-pregn-4-en-3,20-diones, which are then converted to 21-monoiodides and 21-aceta
SYNTHESIS OF THE 21-ACETATE OF SUBSTANCE S FROM 17α-HYDROXYPROGESTERONE
Ryakhovskaya, M. I.,Popova, E. V.,Andryushina, V. A.,Grinenko, G. S.
, p. 839 - 842 (2007/10/02)
-
Simple Route for Elaboration of the Hydroxy-ketone and Dihydroxy-acetone Side-chains of Corticosteroids from 17-Oxo-steroids
Nedelec, Lucien,Torelli, Vesperto,Hardy, Michel
, p. 775 - 777 (2007/10/02)
α-Formylaminoacrylic esters, produced by the condensation of ethyl isocyanoacetate with 17-oxo-steroids have been reduced selectively to give the corresponding alcohols; the latter gave, in high yield, the hydroxyacetyl side-chain on acidic hydrolysis or the dihydroxy-acetone side-chain after appropriate oxidation and hydrolysis.