180740-69-6Relevant articles and documents
Aluminium-mediated reductive dimerization of aromatic dialdehydes
Sahade, Daniel A.,Kawaji, Takatoshi,Sawada, Tsuyoshi,Mataka, Shuntaro,Thiemann, Thies,Tsukinoki, Takehito,Tashiro, Masashi
, p. 210 - 211 (1999)
Pinacol coupling reaction of several aromatic dialdehydes 1a-d using inexpensive aluminum powder as a reductive reagent in aqueous NaOH-methanol media afforded dimeric compounds 2a-d as main products, in which only one carbonyl group of 1 was reduced.
Pincer iridium(III)-catalyzed enantioselective C(sp3)-H functionalization via carbenoid C[sbnd]H insertion of 3-diazooxindoles with 1,4-cyclohexadiene
Gong, Junfang,Li, Nan,Song, Maoping,Wang, Fang,Yang, Xiaoyan,Zhu, Yanyan
supporting information, (2021/12/20)
The asymmetric carbenoid C[sbnd]H insertion of 3-diazooxindoles into 1,4-cyclohexadiene has been accomplished in the presence of chiral bis(imidazoline) NCN pincer iridium(III) complexes as the catalysts. With a catalyst loading of 0.5 mol%, the reactions proceeded smoothly at 0 °C to afford a variety of chiral 3-substituted oxindoles in good yields with moderate to excellent enantioselectivities (up to 99% ee). The protocol exhibits good functional group tolerance with respect to 3-diazooxindoles and is readily scaled up to 2 mmol scale without any loss in activity and enantioselectivity. Density functional theory (DFT) calculations have been performed to better understand the reaction mechanism and to explain the stereochemical outcome of the reactions.
C3-Symmetric chiral trisimidazoline: The role of a third imidazoline and its application to the nitro Michael reaction and the α-amination of β-ketoesters
Murai, Kenichi,Fukushima, Shunsuke,Nakamura, Akira,Shimura, Masato,Fujioka, Hiromichi
, p. 4862 - 4868 (2011/08/03)
We describe the necessity of the C3-symmetry and the role of a third imidazoline of trisimidazoline 3, which was recently developed by us as a new entry of organocatalyst. The utility of 3 as a Br?nsted base catalyst in the nitro Michael reaction and the α-amination of β-ketoesters was shown, and the recyclability of the catalyst was also demonstrated.