18102-22-2

Basic information

• Product Name: 1-(Chloromethyl)-2,5-dimethyl-3-nitrobenzene
• Synonyms: 1-(Chloromethyl)-2,5-dimethyl-3-nitrobenzene
• CAS NO: 18102-22-2
• Molecular Formula: C₉H₁₀ClNO₂
• Molecular Weight: 199.6342
• Mol File: 18102-22-2.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-(Chloromethyl)-2,5-dimethyl-3-nitrobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(Chloromethyl)-2,5-dimethyl-3-nitrobenzene(18102-22-2)
• EPA Substance Registry System: 1-(Chloromethyl)-2,5-dimethyl-3-nitrobenzene(18102-22-2)

Safety Data

• Hazardous Substances Data: 18102-22-2(Hazardous Substances Data)

Usage

Description

1-(Chloromethyl)-2,5-dimethyl-3-nitrobenzene is a chemical compound characterized by a benzene ring with a nitro group and two methyl groups attached at the 2nd and 5th positions. Additionally, a chloromethyl group is attached to the benzene ring, which contributes to its reactivity and potential applications in various chemical processes.

Uses

Used in Pharmaceutical Industry:
1-(Chloromethyl)-2,5-dimethyl-3-nitrobenzene is used as an intermediate in the synthesis of various pharmaceutical compounds for its ability to be further modified and incorporated into drug molecules. Its presence in the molecule can influence the pharmacological properties, such as solubility, stability, and bioavailability of the final drug product.
Used in Pesticide Industry:
In the pesticide industry, 1-(Chloromethyl)-2,5-dimethyl-3-nitrobenzene is used as a precursor in the production of certain pesticides. Its chemical structure can be tailored to create active ingredients that target specific pests, contributing to the development of more effective and selective pest control agents.
Used in Dye Industry:
1-(Chloromethyl)-2,5-dimethyl-3-nitrobenzene is utilized in the dye industry for the synthesis of various organic dyes. Its chemical structure allows for the creation of dyes with specific color properties and stability, which are important for applications in textiles, printing, and other industries that require colorants.
Safety Considerations:
Due to its potential to cause skin and eye irritation, and harmful effects if inhaled or ingested, 1-(Chloromethyl)-2,5-dimethyl-3-nitrobenzene is considered hazardous. It should be handled with care, using appropriate personal protective equipment and following safety protocols to minimize exposure and potential health risks.

Upstream product

• 50-00-0 formaldehyd 
• 89-58-7 mononitro-p-xylene 

Downstream Products

• 57411-95-7 3-Cyanomethyl-2,5-dimethylnitrobenzol 
• 57411-96-8 3-Cyanomethyl-2,5-dimethylanilin 
• 57411-98-0 2,5-Dimethyl-3-hydrazino-phenylacetonitril 
• 69022-52-2 dimethyl-2,5 nitro-3 benzaldehyde 
• 69022-53-3 trans-2,5-dimethyl-3-nitrocinnamic acid 
• 69022-55-5 3-acetamido-2,5-dimethylcinnamic acid 
• 69022-56-6 3-acetamido-2,5-dimethylcinnamoyl azide 

Relevant articles and documents

HETEROAROMATIC MODULATORS OF THE RETINOID-RELATED ORPHAN RECEPTOR GAMMA

The present invention relates to a compound according to general formula (I) wherein X represents N or CH; R1 is -CN, (C1-C6)alkyl, (C3-C7)cycloalkyl, (3-7 membered)heterocycloalkyl, (5-6 membered)heteroaryl, (C3-C7)cycloalkyl(C1-C4)alkyl, (3-7 membered)heterocycloalkyl-(C1-C4)alkyl or (5-6 membered)heteroaryl- (C1-C4)alkyl; R2 is halogen, cyano, (C1-C4)alkyl or (C3-C7)cycloalkyl; R3 is halogen, cyano, (C1-C4)alkyl, (C1-C4)haloalkyl or (C3-C7)cycloalkyl; R4 is (C1-C4)alkyl or (C1-C4)haloalkyl; R5 is (C1-C6)alkyl, (C3-C7)cycloalkyl, (C1-C6)alkyl-(C3-C7)cycloalkyl, (C3-C7)cycloalkyl-(C1-C6)alkyl, (3-7 membered)heterocycloalkyl, phenyl, (5-6 membered)heteroaryl or -ORa. The invention further relates to said compounds for use in therapy, to pharmaceutical compositions comprising said compounds and to intermediates for preparation of said compounds.

Synthesis of potential antineoplastic agents. XXV. Approaches to the pyridocarbazole system

-