181214-43-7

Basic information

• Product Name: Benzene, (4,4-dibromo-3-buten-1-ynyl)-
• CAS NO: 181214-43-7
• Molecular Formula: C10H6Br2
• Molecular Weight: 285.966
• Mol File: 181214-43-7.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Benzene, (4,4-dibromo-3-buten-1-ynyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, (4,4-dibromo-3-buten-1-ynyl)-(181214-43-7)
• EPA Substance Registry System: Benzene, (4,4-dibromo-3-buten-1-ynyl)-(181214-43-7)

Safety Data

• Hazardous Substances Data: 181214-43-7(Hazardous Substances Data)

Upstream product

• 2579-22-8 Phenylpropargyl aldehyde 
• 116-17-6 triisopropyl phosphite 
• 558-13-4 carbon tetrabromide 
• 536-74-3 phenylacetylene 
• 1504-58-1 3-Phenyl-2-propyn-1-ol 
• 56506-90-2 (dibromomethyl)(triphenyl)phosphonium bromide 

Downstream Products

• 1402435-24-8 3-(phenylbuta-1,3-diyn-1-yl)cyclohex-2-enone 
• 1402434-99-4 (S)-3-ethyl-3-(phenylbuta-1,3-diyn-1-yl)cyclohexanone 
• 155187-28-3 trimethyl[(3Z)-6-phenylhex-3-ene-1,5-diynyl]silane 
• 32251-82-4 3-benzyl-1H-pyrazole 
• 204651-50-3 [(Z)-4-iodobut-3-en-1-ynyl]benzene 
• 60214-15-5 7-phenyl-hepta-2,4,6-triyn-1-ol 
• 919087-41-5 (Z)-1-(tert-butyldimethylsilyloxy)-4-bromo-7-phenyl-4-heptene-2,6-diyne 
• 181214-48-2 [(Z)-4-bromobut-3-en-1-ynyl]benzene 

Relevant articles and documents

The application of a monolithic triphenylphosphine reagent for conducting Ramirez gem-dibromoolefination reactions in flow

The application of a monolithic form of triphenylphosphine to the Ramirez gem-dibromoolefination reaction using flow chemistry techniques is reported. A variety of gem-dibromides were synthesised in high purity and excellent yield following only removal of solvent and no further off-line purification. It is also possible to perform the Appel reaction using the same monolith and the relationship between the mechanisms of the two reactions is discussed.

Domino Cu-catalyzed C-N coupling/hydroamidation: A highly efficient synthesis of nitrogen heterocycles

(Chemical Equation Presented) Working in tandem: Highly functionalized pyrroles and pyrazoles can be synthesized from a domino Cu-catalyzed C-N coupling/hydroamidation sequence. The scope and the generality of the method is noteworthy as a wide variety of substituents, either in the alkene or alkyne counterparts, are well tolerated.

One-pot conversion of activated alcohols into 1,1-dibromoalkenes and terminal alkynes using tandem oxidation processes with manganese dioxide

Approaches to the preparation of C1-homologated dibromoalkenes and terminal alkynes from activated alcohols using one-pot tandem oxidation processes (TOPs) with manganese dioxide are outlined. The conversion of alcohols into dibromoalkenes is described using dibromomethyltriphenylphosphonium bromide and the formation of terminal alkynes was achieved via a sequential one-pot, two-step process utilising the Bestmann-Ohira reagent.