181305-63-5

Basic information

• Product Name: 2-fluoro-4-methoxyphenyl acetate
• Synonyms: 2-fluoro-4-methoxyphenyl acetate
• CAS NO: 181305-63-5
• Molecular Weight: 184.167
• Mol File: 181305-63-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-fluoro-4-methoxyphenyl acetate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-fluoro-4-methoxyphenyl acetate(181305-63-5)
• EPA Substance Registry System: 2-fluoro-4-methoxyphenyl acetate(181305-63-5)

Safety Data

• Hazardous Substances Data: 181305-63-5(Hazardous Substances Data)

Upstream product

• 456-49-5 1-fluoro-3-methoxybenzene 
• 64-19-7 acetic acid 
• 74457-86-6 1-(2-fluoro-4-methoxyphenyl)-1-ethanone 

Downstream Products

• 181305-44-2 1-(5-Chloro-pyridin-2-yl)-3-[2-(3-ethoxy-2-fluoro-6-methoxy-phenyl)-ethyl]-thiourea 
• 1026500-31-1 1-Ethoxy-2-fluoro-4-methoxy-3-((E)-2-nitro-vinyl)-benzene 
• 1025884-03-0 3-Ethoxy-2-fluoro-6-methoxyphenethylamine 
• 1027198-33-9 3-Ethoxy-2-fluoro-6-methoxy-benzaldehyde 
• 1026793-94-1 2-ethoxy-1-fluoro-4-methoxybenzene 
• 167683-93-4 2-fluoro-4-methoxy-phenol 

Relevant articles and documents

Direct Acetoxylation of Arenes

Acetoxylation of arenes is an important reaction and an unmet need in chemistry. We report a metal-free, direct acetoxylation reaction using sodium nitrate under an anhydrous environment of trifluoroacetic acid, acetic acid, and acetic anhydride. Arenes (31 examples), with oxidation potentials (Eox, in V vs SCE) lower than benzene (2.48 V), were acetoxylated with good yields and regioselectivity. A stepwise, single electron-transfer mechanism is proposed.