181479-31-2

Basic information

• Product Name: (9-{(2R,5S)-5-[Dimethyl-(1,1,2-trimethyl-propyl)-silanyloxymethyl]-tetrahydro-furan-2-yl}-9H-purin-6-yl)-carbamic acid benzyl ester
• CAS NO: 181479-31-2
• Molecular Weight: 511.696
• Mol File: 181479-31-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (9-{(2R,5S)-5-[Dimethyl-(1,1,2-trimethyl-propyl)-silanyloxymethyl]-tetrahydro-furan-2-yl}-9H-purin-6-yl)-carbamic acid benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (9-{(2R,5S)-5-[Dimethyl-(1,1,2-trimethyl-propyl)-silanyloxymethyl]-tetrahydro-furan-2-yl}-9H-purin-6-yl)-carbamic acid benzyl ester(181479-31-2)
• EPA Substance Registry System: (9-{(2R,5S)-5-[Dimethyl-(1,1,2-trimethyl-propyl)-silanyloxymethyl]-tetrahydro-furan-2-yl}-9H-purin-6-yl)-carbamic acid benzyl ester(181479-31-2)

Safety Data

• Hazardous Substances Data: 181479-31-2(Hazardous Substances Data)

Upstream product

• 4097-22-7 2',3'-Dideoxyadenosine 
• 67373-56-2 chlorodimethyl(1,1,2-trimethylpropyl)silane 
• 501-53-1 benzyl chloroformate 
• 181479-29-8 9-{(2R,5S)-5-[Dimethyl-(1,1,2-trimethyl-propyl)-silanyloxymethyl]-tetrahydro-furan-2-yl}-9H-purin-6-ylamine 

Downstream Products

• 181479-34-5 Hexadecanoic acid (2S,5R)-5-(6-benzyloxycarbonylamino-purin-9-yl)-tetrahydro-furan-2-ylmethyl ester 
• 129533-29-5 2,2-Dimethyl-propionic acid (2S,5R)-5-(6-benzyloxycarbonylamino-purin-9-yl)-tetrahydro-furan-2-ylmethoxymethyl ester 
• 129533-46-6 [9-((2R,5S)-5-Hydroxymethyl-tetrahydro-furan-2-yl)-9H-purin-6-yl]-carbamic acid benzyl ester 

Relevant articles and documents

Ether, carbonate and urethane deoxynucleoside derivatives as prodrugs

3′-Deoxythymidine and its 3′-azido derivative, 2′,3′-dideoxycytidine, 2′,3′-dideoxyinosine and 2′,3′-dideoxyadenosine have been acylated to form carbonates and urethanes in chemoselective reactions. The nucleosides have been N- and/or O-alkylated by α-chl