181637-40-1

Basic information

• Product Name: (2R)-N-triphenylmethyl-3-iodoalanine methyl ester
• Synonyms: (2R)-N-triphenylmethyl-3-iodoalanine methyl ester
• CAS NO: 181637-40-1
• Molecular Weight: 471.338
• Mol File: 181637-40-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (2R)-N-triphenylmethyl-3-iodoalanine methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (2R)-N-triphenylmethyl-3-iodoalanine methyl ester(181637-40-1)
• EPA Substance Registry System: (2R)-N-triphenylmethyl-3-iodoalanine methyl ester(181637-40-1)

Safety Data

• Hazardous Substances Data: 181637-40-1(Hazardous Substances Data)

Upstream product

• 76357-12-5 (S)-methyl3-((methylsulfonyl)oxy)-2-(tritylamino)propanoate 
• 13515-76-9 methyl N-trityl-L-serinate 

Downstream Products

• 181637-47-8 methyl (2S)-4,4-dicyano-2-(tritylamino)butanoate 
• 75154-68-6 methyl (2S)-N-tritylaziridine-2-carboxylate 
• 181637-42-3 (S)-1,5,5'-trimethyl-N-(triphenylmethyl)-4-carboxyglutamate 
• 67413-25-6 benzyl (-)-(2S)-1-trityl-aziridine-2-carboxylate 
• 191993-94-9 (R)-3-((R)-2-tert-Butoxycarbonylamino-2-methoxycarbonyl-ethylsulfanyl)-2-(trityl-amino)-propionic acid methyl ester 

Relevant articles and documents

The stereospecific synthesis of 'orthogonally' protected lanthionines

Lanthionine is an attractive monomer for the design and synthesis of novel conformationally constrained peptidomimetics, since unlike cystine, the monosulfur bridge of lanthionine is chemically far more robust and also displays a greater degree of conformational rigidity. The synthesis of lanthionine residues for use in peptide synthesis is non-trivial due to the protectional requirements necessary for this tetra-functional amino acid. In this paper an efficient stereo-specific route to orthogonally protected lanthionine is described.

Stereoconservative synthesis of orthogonally protected γ-functionalized amino acids using N-tritylserine derivatives

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