181648-03-3

Basic information

• Product Name: [3-2H₂]nordiazepam 4-oxide
• CAS NO: 181648-03-3
• Molecular Weight: 288.702
• Mol File: 181648-03-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: [3-2H₂]nordiazepam 4-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: [3-2H₂]nordiazepam 4-oxide(181648-03-3)
• EPA Substance Registry System: [3-2H₂]nordiazepam 4-oxide(181648-03-3)

Safety Data

• Hazardous Substances Data: 181648-03-3(Hazardous Substances Data)

Upstream product

• 963-39-3 demoxepam 

Downstream Products

• 51278-96-7 <3-2H2>nordiazepam 
• 181648-04-4 [3-2H]oxazepam 3-acetate 

Relevant articles and documents

Synthesis of 3-deuterated diazepam and nordiazepam 4-oxides and their use in the synthesis of other 3-deuterated derivatives

The protons at 3-positions of diazepam 4-oxide and nordiazepam 4-oxide underwent an efficient deuterium exchange via keto-enol tautomerism in deuterated alkaline methanol. The 3-dideuterated 4-oxides were each used as a starting material to synthesize 3-monodeuterated oxazepam and its 3-acetate, 3-monodeuterated temazepam and its 3-acetate, and 3-dideuterated diazepam and nordiazepam.