181648-42-0

Basic information

• Product Name: tert-butyl-(4-chloro-3-methyl-phenoxy)-dimethyl-silane
• Synonyms: tert-butyl-(4-chloro-3-methyl-phenoxy)-dimethyl-silane
• CAS NO: 181648-42-0
• Molecular Weight: 256.848
• Mol File: 181648-42-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: tert-butyl-(4-chloro-3-methyl-phenoxy)-dimethyl-silane(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl-(4-chloro-3-methyl-phenoxy)-dimethyl-silane(181648-42-0)
• EPA Substance Registry System: tert-butyl-(4-chloro-3-methyl-phenoxy)-dimethyl-silane(181648-42-0)

Safety Data

• Hazardous Substances Data: 181648-42-0(Hazardous Substances Data)

Upstream product

• 59-50-7 4-Chloro-3-methylphenol 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 288-32-4 1H-imidazole 
• 18113-07-0 4-Chloro-3-methoxyphenol 

Downstream Products

• 954367-88-5 4-(tert-butyl-dimethylsiloxy)-2,2',5'-trimethyl-biphenyl 
• 62790-75-4 1-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-3-methylbenzene 
• 181648-48-6 {(E)-6-[5-(tert-Butyl-dimethyl-silanyloxy)-2-chloro-phenyl]-hex-3-enyl}-carbamic acid ethyl ester 
• 181648-56-6 (E)-1-[6-(2-chloro-5-methoxyphenyl)-3-hexenyl]-5-ethoxy-2-pyrrolidinone 
• 181648-55-5 (E)-1-[6-(2-chloro-5-methoxyphenyl)-3-hexenyl]-2,5-pyrrolidinedione 
• 181648-40-8 (E)-[6-(2-chloro-5-methoxyphenyl)-3-hexenyl]carbamic acid ethyl ester 
• 181648-57-7 (E)-7-[5-(tert-Butyl-dimethyl-silanyloxy)-2-chloro-phenyl]-hept-4-enoic acid ethyl ester 
• 181648-47-5 (E)-7-[5-(tert-Butyl-dimethyl-silanyloxy)-2-chloro-phenyl]-hept-4-enoic acid 
• 181648-44-2 3-[5-(tert-Butyl-dimethyl-silanyloxy)-2-chloro-phenyl]-propionic acid ethyl ester 
• 181648-46-4 5-[5-(tert-Butyl-dimethyl-silanyloxy)-2-chloro-phenyl]-pent-1-en-3-ol 
• 181648-53-3 (E)-[6-(2-chloro-5-methoxyphenyl)-3-hexenyl]amine 
• 181648-45-3 3-[5-(tert-Butyl-dimethyl-silanyloxy)-2-chloro-phenyl]-propionaldehyde 
• 181648-41-9 3-[5-(tert-Butyl-dimethyl-silanyloxy)-2-chloro-phenyl]-propan-1-ol 
• 181648-43-1 [3-(bromomethyl)-4-chlorophenoxy](tert-butyl)dimethylsilane 

Relevant articles and documents

Synthesis of an azasteroid using an acyl iminium ion-initiated tandem cyclization

An acyl iminium ion-initiated tandem cyclization gave an unexpected dienone product, a secoazasteroid (2). The factors governing the formation of 2 were investigated in an attempt to optimize its formation. The reaction was applied to a more elaborate system, resulting in the synthesis of the full steroid skeleton of 13-azaandrosta-1,4-diene-3,17-dione (3), which contains the unusual substitution of a chlorine atom for the axial 19-methyl.