181819-75-0

Basic information

• Product Name: (4-(methylamino)phenyl)methanol
• Synonyms: (4-(methylamino)phenyl)methanol;4-(Methylamino)benzenemethanol
• CAS NO: 181819-75-0
• Molecular Formula: C₈H₁₁NO
• Molecular Weight: 137.17904
• Mol File: 181819-75-0.mol
• Article Data: 13

Chemical Properties

• Melting Point: 68-70 °C(Solv: benzene (71-43-2))
• Boiling Point: 282.4±23.0 °C(Predicted)
• Appearance: /
• Density: 1.117±0.06 g/cm3(Predicted)
• PKA: 14.89±0.10(Predicted)
• CAS DataBase Reference: (4-(methylamino)phenyl)methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (4-(methylamino)phenyl)methanol(181819-75-0)
• EPA Substance Registry System: (4-(methylamino)phenyl)methanol(181819-75-0)

Safety Data

• Hazardous Substances Data: 181819-75-0(Hazardous Substances Data)

Usage

General Description

(4-(methylamino)phenyl)methanol, also known as 4-(methylamino)benzyl alcohol, is a chemical compound with the molecular formula C9H13NO. It is a colorless liquid with a faint odor, and it is commonly used as a precursor in the synthesis of pharmaceuticals and other organic compounds. The compound has the potential to be hazardous if not handled properly, and it should be stored and handled according to appropriate safety guidelines. Additionally, it is important to be aware of its potential health effects, including skin and eye irritation, and to take proper precautions when working with this chemical.

Upstream product

• 67-56-1 methanol 
• 66493-39-8 4-(N-tert-butoxycarbonyl)aminobenzoic acid 
• 150-13-0 4-amino-benzoic acid 
• 623-04-1 4-aminobenzenemethanol 
• 616-38-6 carbonic acid dimethyl ester 
• 10541-83-0 N-methyl-p-aminobenzoic acid 
• 18358-63-9 methyl 4-(N-methyl)aminobenzoate 
• 402943-23-1 N-{(4-{methyl[(4-nitrophenoxy)carbonyl]amino}benzyloxy)carbonyl}-L-tryptophan 

Downstream Products

• 1254102-47-0 4-((tert-butyldimethylsilyloxy)-N-methylamino)benzyl alcohol 
• 1609626-97-2 C₃₉H₄₁N₃O₇ 
• 1609626-96-1 C₂₈H₄₁NO₄Si 
• 1426551-45-2 N-(4-(hydroxymethyl)phenyl)-N,3-dimethyl-3-(2,4,5-trimethyl-3,6-dioxocyclohexa-1,4-dien-1-yl)butanamide 
• 1426551-42-9 N-(4-(hydroxymethyl)phenyl)-3-methyl-3-(2,4,5-trimethyl-3,6-dioxocyclohexa-1,4-dien-1-yl)butanamide 
• 623-08-5 N-methyl-p-toluidine 
• 1089681-69-5 (E)-4-(2-(6-methoxybenzofuran-2-yl)vinyl)-N-methylaniline 
• 780821-17-2 (4-formylphenyl)(methyl)carbamic acid tert-butyl ester 
• 1089682-48-3 (E)-tert-butyl (4-(2-(6-methoxybenzofuran-2-yl)vinyl)phenyl)(methyl)carbamate 
• 1462470-44-5 (E)-6-(methoxy)-2-(4,4′-methyl(2-fluoroethyl)aminostyryl)benzofuran 
• 172353-84-3 tert-butyl((4-hydroxymethyl)phenyl)(methyl)carbamate 
• 929896-96-8 4-[N-(dichloroacetyl)-N-methylamino]benzyl alcohol 
• 1020100-95-1 5'-O-(4,4'-dimethoxytrityl)-3'-O-[(N,N-diisopropylamino)(2-cyanoethyloxy)phosphinyl]-2'-O-[4-(N-dichloroacetyl-N-methylamino)benzyloxy]methyluridine 
• 1020100-92-8 5'-O-(4,4'-dimethoxytrityl)-2'-O-[[[4-[N-(dichloroacetyl)-N-methylamino]benzyl]oxy]methyl]uridine 

Relevant articles and documents

A reversible reaction inside a self-assembled capsule

Reversible encapsulation allows the direct observation of the isolated molecules under ambient conditions, at equilibrium and in the liquid phase. Here we show that capsules can amplify and stabilize molecules that are present in only trace concentrations

N-Alkylation of Alkylolamines with Alcohols Over Mesoporous Solid Acid–Base Cs–B–Zr Catalyst

Abstract: The mesoporous solid acid–base Cs–B–Zr mixed oxides were synthesized using the co-precipitation method followed by a subsequent thermal treatment. The catalytic activity of solid Cs–B–Zr mixed oxide was tested for solvent free acid–base catalysed direct alkylolamines with alcohols as green alkylating agent. The effects of Cs/B/Zr ratio, calcination temperature, reaction conditions, and reaction substrate on the catalytic performance of the catalysts were investigated. The XRD, N2 adsorption–desorption, ICP-OES, FT-IR and NH3/CO2-TPD results showed that the mesoporous structure and acid–base properties of the catalysts play important roles in the reaction. A suitable number of acid and basic sites on the catalyst lead to a high activity for the N-alkylation reaction. Graphical Abstract: A direct N-alkylation of amino alcohol with alcohols has been developed using mixed oxide Cs–B–Zr as an acid–base bifunctionalized catalyst.[Figure not available: see fulltext.]

NEW CYCLOHEXYL AND QUINUCLIDINYL CARBAMATE DERIVATIVES HAVING BETA2 ADRENERGIC AGONIST AND M3 MUSCARINIC ANTAGONIST ACTIVITY

The present invention relates to novel compounds having β2 adrenergic agonist and M3 muscarinic antagonist dual activity, to pharmaceutical compositions containing them, to the process for their preparation and to their use in respiratory therapies.