18207-47-1

Basic information

• Product Name: Ethanone, 2,2,2-trifluoro-1-(2-furanyl)- (9CI)
• Synonyms: Ethanone, 2,2,2-trifluoro-1-(2-furanyl)- (9CI);2,2,2-Trifluoro-1-(2-furyl)ethanone;2-Furyl trifluoromethyl ketone;Ethanone,2,2,2-trifluoro-1-(2-furanyl)-;2,2,2-Trifluoro-1-(furan-2-yl)
• CAS NO: 18207-47-1
• Molecular Formula: C₆H₃F₃O₂
• Molecular Weight: 164.0820296
• Product Categories: ACETYLHALIDE
• Mol File: 18207-47-1.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 144℃
• Flash Point: 41℃
• Appearance: /
• Density: 1.365
• Vapor Pressure: 5.12mmHg at 25°C
• Refractive Index: 1.398
• CAS DataBase Reference: Ethanone, 2,2,2-trifluoro-1-(2-furanyl)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 2,2,2-trifluoro-1-(2-furanyl)- (9CI)(18207-47-1)
• EPA Substance Registry System: Ethanone, 2,2,2-trifluoro-1-(2-furanyl)- (9CI)(18207-47-1)

Safety Data

• Hazardous Substances Data: 18207-47-1(Hazardous Substances Data)

Usage

General Description

Ethanone, 2,2,2-trifluoro-1-(2-furanyl)- (9CI) is a specialized chemical compound defined by its unique structure incorporating an ethanone group, a trifluoro group, and a furanyl group. Ethanone, 2,2,2-trifluoro-1-(2-furanyl)- (9CI), often used in the production of other chemical compounds, has been of interest in scientific research due to its unique characteristics. The presence of the trifluoro group can significantly influence the compound's reactivity and properties, making the compound useful in many industrial applications. It is also known by its Chemical Abstracts Service (CAS) registry number 674-85-7. As with any chemical compound, it should be handled appropriately to ensure safety and prevent harm.

InChI:InChI=1/C6H3F3O2/c7-6(8,9)5(10)4-2-1-3-11-4/h1-3H

Upstream product

• 110-00-9 furan 
• 407-25-0 trifluoroacetic anhydride 
• 98-01-1 furfural 
• 527-69-5 2-furancarbonyl chloride 
• 81290-20-2 (trifluoromethyl)trimethylsilane 
• 70783-48-1 2-(2,2,2-trifluoro-1-hydroxyethyl)furan 
• 110-86-1 pyridine 

Downstream Products

• 1333475-68-5 (S)-4-methyl N-(2,2,2-trifluoro-1-(furan-2-yl)ethylidene)benzenesulfinamide 
• 1333475-81-2 C₁₉H₁₄F₃NO₂ 

Relevant articles and documents

A facile synthesis of aryl trifluoromethyl ketones

The reaction of arylcopper reagents with α,α,α-trifluoroacetic anhydride gives the corresponding aryl trifluoromethyl ketones in good yields.

Enhancements of Trifluoroacetic Acylated Five-membered Heterocyclic Compounds Using as Additives in Dye Sensitized Solar Cells

In this study, five-membered heterocyclic compounds are trifluoroacetic acylated for the purpose of providing more long pairs to enhance electrolyte in dye sensitized solar cells (DSSCs). Four five-membered heterocyclic compounds will be trifluoroacetic acylated with trifluoroacetic anhydride by Friedel-Crafts acylation: furan, thiophene, pyrrole and N-methylpyrrole. The properties will be measured by cyclic voltage (CV), Fourier transform infrared spectroscopy (FTIR), solar simulator, and electrochemical impedance spectroscopy (EIS). We find out that furan and thiophene which we add in electrolyte as additives can increase short circuit current and photovoltaic efficiency, and furthermore, all the trifluoroacetic acylated heterocyclic compounds perform better photoelectric abilities than non-trifluoroacetic acylated one. The photovoltaic efficiency will be increased from 4.439% to 5.197% when 1wt% trifluoroacetic acylated thiophene is added in electrolyte as additives.

THIADIAZOLES AS CXC- AND CC- CHEMOKINE RECEPTOR LIGANDS

Disclosed are novel compounds of Formula (IA) and the pharmaceutically acceptable salts and solvates thereof. Examples of groups comprising Substituent A include heteroaryl, aryl, heterocycloalkyl, cycloalkyl, aryl, alkynyl, alkenyl, aminoalkyl, alkyl or amino. Examples of groups comprising Substituent B include aryl and heteroaryl. Also disclosed is a method of treating a chemokine mediated diseases, such as, cancer, angiogenisis, angiogenic ocular diseases, pulmonary diseases, multiple sclerosis, rheumatoid arthritis, osteoarthritis, stroke and ischemia reperfusion injury, pain (e.g., acute pain, acute and chronic inflammatory pain, and neuropathic pain) using a compound of Formula (IA).