182120-90-7 Usage
Chemical class
Oxazole derivatives
Explanation
The compound belongs to the oxazole class of molecules, which are characterized by a five-membered ring with one oxygen and two nitrogen atoms.
Explanation
2-((Tert-butoxycarbonylamino)methyl)oxazole-4-carboxylic acid is derived from oxazole-4-carboxylic acid, which is a core structure of the molecule.
Explanation
This group is attached to the methyl group of the oxazole ring, which consists of a tert-butyl group (C4H9) and a carbonyl group (C=O).
Explanation
The compound contains a carboxylic acid functional group (-COOH) at the 4-position of the oxazole ring, which is responsible for its acidic properties.
Explanation
2-((Tert-butoxycarbonylamino)methyl)oxazole-4-carboxylic acid may be used in the development of pharmaceuticals due to its unique structure and properties.
Explanation
The compound can be used as a building block or intermediate in the synthesis of other organic compounds, expanding its potential applications in various fields.
Explanation
Further research is needed to fully understand the properties and potential uses of 2-((Tert-butoxycarbonylamino)methyl)oxazole-4-carboxylic acid, as its applications and behavior in different conditions are not yet fully explored.
Parent compound
Oxazole-4-carboxylic acid
Substituent
tert-Butoxycarbonylamino group
Functional groups
Carboxylic acid
Potential applications
Medicinal chemistry
Synthesis
Organic compound synthesis
Research status
Ongoing
Check Digit Verification of cas no
The CAS Registry Mumber 182120-90-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,2,1,2 and 0 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 182120-90:
(8*1)+(7*8)+(6*2)+(5*1)+(4*2)+(3*0)+(2*9)+(1*0)=107
107 % 10 = 7
So 182120-90-7 is a valid CAS Registry Number.
InChI:InChI=1/C10H14N2O5/c1-10(2,3)17-9(15)11-4-7-12-6(5-16-7)8(13)14/h5H,4H2,1-3H3,(H,11,15)(H,13,14)
182120-90-7Relevant articles and documents
Late-Stage Macrocyclization of Bioactive Peptides with Internal Oxazole Motifs via Palladium-Catalyzed C-H Olefination
Liu, Shu,Cai, Chuangxu,Bai, Zengbing,Sheng, Wangjian,Tan, Jiantao,Wang, Huan
, p. 2933 - 2937 (2021)
Oxazole is an important pharmacophore and exists in the backbone of many bioactive peptide natural products and peptidomimetics. Efficient methods for the synthesis and direct functionalization of complex oxazole-containing peptides are in high demand. Herein, we report the late-stage site-selective functionalization of oxazole-containing peptides via palladium-catalyzed δ-C(sp2)-H olefination of phenylalanine, tryptophan, and tyrosine residues. This strategy utilizes oxazole motifs as internal directing groups and provides access to oxazole-containing peptide macrocycles with bioactivities.
NOVEL FERROPORTIN INHIBITORS
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Page/Page column 137; 138; 187; 263, (2017/05/10)
The invention relates to novel ferroportin inhibitors of the general formula (I) pharmaceutical compositions comprising them and the use thereof as medicaments, in particular for the prophylaxis and/or treatment of diseases caused by a lack of hepcidin or iron metabolism disorders, such as particularly iron overload states such as in particular thalassemia and hemochromatosis.
Method for preparing largazole analogs and uses thereof
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Page/Page column 37, (2010/03/02)
Analogs of largazole are described herein. Methods of treating cancer and blood disorders using largazole and largazole analogs and pharmaceutical compositions comprising the same are additionally described herein. Methods for preparing largazole analogs are likewise described.
