182145-40-0

Basic information

• Product Name: N-[2-(1-Hydroxyhept-6-enyl)phenyl]-4-methylbenzenesulfonamide
• CAS NO: 182145-40-0
• Molecular Weight: 359.489
• Mol File: 182145-40-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-[2-(1-Hydroxyhept-6-enyl)phenyl]-4-methylbenzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[2-(1-Hydroxyhept-6-enyl)phenyl]-4-methylbenzenesulfonamide(182145-40-0)
• EPA Substance Registry System: N-[2-(1-Hydroxyhept-6-enyl)phenyl]-4-methylbenzenesulfonamide(182145-40-0)

Safety Data

• Hazardous Substances Data: 182145-40-0(Hazardous Substances Data)

Upstream product

• 6590-65-4 N-(2-Formyl-phenyl)-4-methyl-benzenesulfonamide 
• 2695-47-8 6-Bromo-1-hexene 

Downstream Products

• 182145-48-8 4-Hex-5-enyl-N-(4-methylphenylsulfonyl)-1,4-dihydro-2H-3,1-benzoxazin-2-one 

Relevant articles and documents

Diels-Alder reactions of N-sulfonyl substituted aza-ortho-xylylenes generated from the corresponding 1,4-dihydro-2H-3,1-benzoxazin-2-one derivatives

N-Tosyl- and N-alkylidene-sulfonyl substituted 1,4-dihydro-2A-3,1-benzoxazin-2-ones 2c-g easily undergo thermal carbon dioxide extrusion leading to the aza-ortho-xylylenes 3c-g. The intermediates 3c,d can be trapped by electron-poor ethylenic and acetylenic dienophiles, giving tetrahydroquinoline and quinoline derivatives. The reactions of 2c with non-symmetrical dienophiles are completely regioselective. N-Alkylidenesulfonyl substituted aza-orthro-xylylenes 3f-g undergo intramolecular Diels-Alder reactions leading to the tricyclic compounds 10 and 11, while the aza-ortho-xylylene generated from 4-(hex-5-enyl)-N-(4-methylphenylsulfonyl)-1,4-tetrahydro-2H-3,1-benzoxazin-2-one undergoes a [1,5] hydrogen shift leading to N-[2-(1E)-hepta-1,6-dien-1-ylphenyl]-4-methylbenzenesulfonamide.