182268-24-2Relevant articles and documents
Syntheses of (6S)-cephalosporins from 6-aminopenicillanic acid
Fekner, Tomasz,Baldwin, Jack E,Adlington, Robert M,Jones, Timothy W,Prout, C.Keith,Schofield, Christopher J
, p. 6053 - 6074 (2007/10/03)
Two practical routes to (6S,7S)-cephalosporins from 6-aminopenicillanic acid (6-APA) are described. In the first, 6-APA was converted to (2S,4S,5S,6S)-penicillin sulfoxide 49, which underwent Morin ring expansion to a protected (6S,7S)-cephem 50. In the s