18272-82-7Relevant articles and documents
Barbier–Negishi Coupling of Secondary Alkyl Bromides with Aryl and Alkenyl Triflates and Nonaflates
Zhang, Ke-Feng,Christoffel, Fadri,Baudoin, Olivier
supporting information, p. 1982 - 1986 (2018/02/06)
A mild and practical Barbier–Negishi coupling of secondary alkyl bromides with aryl and alkenyl triflates and nonaflates has been developed. This challenging reaction was enabled by the use of a very bulky imidazole-based phosphine ligand, which resulted in good yields as well as good chemo- and site selectivities for a broad range of substrates at room temperature and under non-aqueous conditions. This reaction was extended to primary alkyl bromides by using an analogous pyrazole-based ligand.
Iron-catalyzed oxidative heterocoupling between aliphatic and aromatic organozinc reagents: A novel pathway for functionalized aryl-alkyl cross-coupling reactions
Cahiez, Gerard,Foulgoc, Laura,Moyeux, Alban
supporting information; scheme or table, p. 2969 - 2972 (2009/09/06)
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COMPOUNDS FOR INHIBITING KSP KINESIN ACTIVITY
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Page/Page column 89; 90, (2010/11/23)
The present invention provides compounds of Formula (I) (wherein R1, R3, X, W, Z and ring Y are as defined herein). The present invention also provides compositions comprising these compounds that are useful for treating cellular proliferative diseases or disorders associated with KSP kinesin activity and for inhibiting KSP kinesin activity.