182815-43-6 Usage
Description
Colesevelam Hydrochloride is a polyallylamine derivative that has been cross-linked with epichlorohydrin and alkylated with 1-bromodecane and 6-bromohexyltrimethylammonium bromide. It is used in its hydrochloride form as a bile acid sequestrant, which helps in reducing the levels of cholesterol and other fatty substances in the blood.
Uses
Used in Pharmaceutical Industry:
Colesevelam Hydrochloride is used as an antihyperlipidemic agent for the treatment of high cholesterol levels. It functions by binding to bile acids in the digestive tract, preventing their reabsorption and promoting their excretion from the body. This process leads to a reduction in the amount of cholesterol and other fatty substances in the blood, thus helping to manage and lower the risk of cardiovascular diseases.
Used in Drug Delivery Systems:
Colesevelam Hydrochloride is also utilized in the development of novel drug delivery systems, particularly for the controlled release of medications. Its unique properties allow for the encapsulation and targeted delivery of various therapeutic agents, enhancing their bioavailability and overall efficacy.
Brand Name:
Welchol (Sankyo) is a well-known brand name under which Colesevelam Hydrochloride is marketed and distributed for the treatment of hyperlipidemia.
Check Digit Verification of cas no
The CAS Registry Mumber 182815-43-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,2,8,1 and 5 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 182815-43:
(8*1)+(7*8)+(6*2)+(5*8)+(4*1)+(3*5)+(2*4)+(1*3)=146
146 % 10 = 6
So 182815-43-6 is a valid CAS Registry Number.