18282-59-2 Usage
Description
1-Bromo-3,4-dichlorobenzene is an organic compound that is colorless to light yellow in appearance. It is a derivative of benzene with a bromine atom at the 1st position and two chlorine atoms at the 3rd and 4th positions. 1-Bromo-3,4-dichlorobenzene is known for its participation in the synthesis of N-arylated sultams, which are important in various chemical and pharmaceutical applications.
Uses
Used in Pharmaceutical Industry:
1-Bromo-3,4-dichlorobenzene is used as a key intermediate in the synthesis of N-arylated sultams for the pharmaceutical industry. These sultams are known for their potential applications in the development of new drugs, particularly in the treatment of various medical conditions.
Used in Chemical Synthesis:
1-Bromo-3,4-dichlorobenzene is also used as a versatile building block in the synthesis of various organic compounds. Its unique structure allows for further functionalization and modification, making it a valuable component in the creation of a wide range of chemical products.
Used in Research and Development:
Due to its reactivity and structural features, 1-Bromo-3,4-dichlorobenzene is often utilized in research and development settings. It serves as a model compound for studying various chemical reactions and exploring new synthetic pathways, contributing to the advancement of chemical science and technology.
Check Digit Verification of cas no
The CAS Registry Mumber 18282-59-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,2,8 and 2 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 18282-59:
(7*1)+(6*8)+(5*2)+(4*8)+(3*2)+(2*5)+(1*9)=122
122 % 10 = 2
So 18282-59-2 is a valid CAS Registry Number.
InChI:InChI=1/C6H3BrCl2/c7-4-1-2-5(8)6(9)3-4/h1-3H
18282-59-2Relevant articles and documents
Metal- and base-free synthesis of aryl bromides from arylhydrazines
Phuc Tran, Dat,Nomoto, Akihiro,Mita, Soichiro,Dong, Chun-ping,Kodama, Shintaro,Mizuno, Takumi,Ogawa, Akiya
supporting information, (2020/05/08)
An efficient method was developed to synthesize brominated aromatic compounds from arylhydrazine hydrochlorides by using BBr3 in DMSO/CPME (cyclopentyl methyl ether) under air at 80 °C for 1 h without the use of bases or metal catalysts. In particular, this method could be carried out satisfactorily using electron-withdrawing groups to afford aryl bromides in a moderate to excellent yields.
One-Pot, Metal-Free Conversion of Anilines to Aryl Bromides and Iodides
Leas, Derek A.,Dong, Yuxiang,Vennerstrom, Jonathan L.,Stack, Douglas E.
supporting information, p. 2518 - 2521 (2017/05/24)
A metal-free synthesis of aryl bromides and iodides from anilines via halogen abstraction from bromotrichloromethane and diiodomethane is described. This one-pot reaction affords aryl halides from the corresponding anilines in moderate to excellent yields without isolation of diazonium salts. The transformation has short reaction times, a simple workup, and insensitivity to moisture and air and avoids excess halogenation. DFT calculations support a SRN1 mechanism. This method represents a convenient alternative to the classic Sandmeyer reaction.
Potential noncataleptic neuroleptic agents: 2,3-dichloro-10-[4-(2-hydroxyethyl)piperazino]-10,11-dihydrodibenzo[b,f]thie pin
Urban,Dlabac,Valchar,Protiva
, p. 992 - 1001 (2007/10/02)
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