18300-68-0 Usage
Description
1-(4-Aminophenyl)ethanone semicarbazone is a chemical compound that features a semicarbazone group attached to a 1-(4-aminophenyl)ethanone molecule. It is recognized for its potential anti-cancer properties and is a subject of interest in pharmaceutical research due to its significant inhibitory effects on colon cancer cell growth.
Uses
Used in Pharmaceutical Research:
1-(4-Aminophenyl)ethanone semicarbazone is used as a research compound for its potential anti-cancer properties. It is particularly noted for its inhibitory effects on colon cancer cell growth, making it a promising candidate for the development of anti-cancer drugs.
Used in Cancer Treatment:
1-(4-Aminophenyl)ethanone semicarbazone is used as a therapeutic agent in the treatment of various types of cancer, including colon cancer, breast cancer, and leukemia. Its chemical structure and properties are being explored for their potential in developing targeted cancer therapies.
Used in Drug Development:
In the pharmaceutical industry, 1-(4-Aminophenyl)ethanone semicarbazone is used as a lead compound in the development of new anti-cancer drugs. Its potential to inhibit cancer cell growth and its chemical properties make it a valuable asset in the creation of novel cancer treatments.
Check Digit Verification of cas no
The CAS Registry Mumber 18300-68-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,3,0 and 0 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 18300-68:
(7*1)+(6*8)+(5*3)+(4*0)+(3*0)+(2*6)+(1*8)=90
90 % 10 = 0
So 18300-68-0 is a valid CAS Registry Number.
18300-68-0Relevant articles and documents
Evaluation of semicarbazones for anticonvulsant and sedative-hypnotic properties
Pandeya,Aggarwal,Jain
, p. 300 - 302 (2007/10/03)
A series of semicarbazones and thiosemicarbazones were synthesized and evaluated for anti-convulsant activity. Some compounds provided significant protection against Maximal Electroshock (MES) and subcutaneous strychnine induced seizures. Compound 1 was the most active in the series with activity in a dose of 30 mg/kg in the strychnine seizure pattern test and an ED50 of 10 mg/kg in the MES test. Hence it could serve as a prototype molecule for future development. Also compounds with a p-nitrophenyl substitution in place of the amino hydrogen of semicarbazone moiety showed activity in a dose of 30 mg/kg and an ED50 of 83 mg/kg in the MES test.
