183270-50-0

Basic information

• Product Name: Benzoic acid, 3-[3-[[2-[[(1,1-dimethylethoxy)carbonyl]amino]-1-oxo-3-[(triphenylmethyl) thio]propyl]amino]phenoxy]-, methyl ester, (R)-
• CAS NO: 183270-50-0
• Molecular Formula: C41H40N2O6S
• Molecular Weight: 688.844
• Mol File: 183270-50-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 3-[3-[[2-[[(1,1-dimethylethoxy)carbonyl]amino]-1-oxo-3-[(triphenylmethyl) thio]propyl]amino]phenoxy]-, methyl ester, (R)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 3-[3-[[2-[[(1,1-dimethylethoxy)carbonyl]amino]-1-oxo-3-[(triphenylmethyl) thio]propyl]amino]phenoxy]-, methyl ester, (R)-(183270-50-0)
• EPA Substance Registry System: Benzoic acid, 3-[3-[[2-[[(1,1-dimethylethoxy)carbonyl]amino]-1-oxo-3-[(triphenylmethyl) thio]propyl]amino]phenoxy]-, methyl ester, (R)-(183270-50-0)

Safety Data

• Hazardous Substances Data: 183270-50-0(Hazardous Substances Data)

Upstream product

• 21947-98-8 N-tert-butyloxycarbonyl-S-trityl-L-cysteine 
• 183270-47-5 3-(3-amino-phenoxy)-benzoic acid methyl ester 
• 645-00-1 m-iodonitrobenzene 
• 19438-10-9 methyl 3-hydroxybenzoate 
• 183270-46-4 3-(3-nitro-phenoxy)-benzoic acid methyl ester 

Downstream Products

• 191281-29-5 3-[3-((R)-2-tert-Butoxycarbonylamino-3-tritylsulfanyl-propionylamino)-phenoxy]-benzoic acid 

Relevant articles and documents

Diarylether inhibitors of farnesyl-protein transferase

The design and synthesis of simple nonpeptide inhibitors of farnesyl-protein transferase (FTase) are described. Cysteine-derived diarylether frameworks are appropriate structural replacements for the C-terminal tetrapeptide portion of the Ras protein, and possess in vitro potency against FTase. Inhibitory activity is dependent on the ring-substitution pattern, and does not require the presence of a C-terminal carboxylate group.