183284-64-2

Basic information

• Product Name: (Z)-1,2-diphenyl-2-(p-tolylimino)ethan-1-one
• Synonyms: (Z)-1,2-diphenyl-2-(p-tolylimino)ethan-1-one
• CAS NO: 183284-64-2
• Molecular Weight: 299.372
• Mol File: 183284-64-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (Z)-1,2-diphenyl-2-(p-tolylimino)ethan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-1,2-diphenyl-2-(p-tolylimino)ethan-1-one(183284-64-2)
• EPA Substance Registry System: (Z)-1,2-diphenyl-2-(p-tolylimino)ethan-1-one(183284-64-2)

Safety Data

• Hazardous Substances Data: 183284-64-2(Hazardous Substances Data)

Upstream product

• 106-49-0 p-toluidine 
• 2327-67-5 N-(p-tolyl)-P,P,P-triphenylphosphine imide 
• 134-81-6 benzil 
• 2101-86-2 p-methylazidobenzene 

Downstream Products

• 5722-91-8 1,2-diphenyl-2-(phenylamino)ethanone 
• 10205-58-0 6-methyl-2-phenyl-1,3-benzothiazole 
• 351217-77-1 7-methyl-2,3-diphenyl-2H-benzo[1,4]thiazine 
• 78604-82-7 α-p-toluidino-deoxybenzoin 
• 856410-28-1 α'-p-toluidino-bibenzyl-α-ol 

Relevant articles and documents

Br?nsted Base-Catalyzed Formal Reductive [3+2] Annulation of 4,4,4-Trifluorocrotonate and α-Iminoketones

A formal reductive [3+2] annulation of 4,4,4-trifluorocrotonate and α-iminoketones was developed under Br?nsted base catalysis. A single phosphazene base efficiently catalyzes the one-pot tandem reaction involving two mechanistically different elementary processes, namely the chemoselective reduction of an imine moiety of α-iminoketones with thiols as the reductant and the subsequent intermolecular Michael addition of an enolate of α-aminoketones concomitant with lactam formation. This operationally simple method provides β-trifluoromethyl-substituted γ-lactams with a tetrasubstituted carbon as a single diastereomer.

Titanium(IV) chloride induced reactions of ketones and C-acylimines with dimethylcyanamide

The reactions of ketones (benzophenone, 4-methylbenzophenone, acetophenone, acetone, and 2,2,4,4-tetramethyl-3-pentanone) and C-acylimines with dimethylcyanamide in the presence of titanium(IV) chloride were investigated. Benzophenone and 4-methylbenzophenone react with dimethylcyanamide to give 4,4-disubstituted 2-dimethylamino-3-aza-1-oxa-1,3-butadienes 5 and 4,4-disubstituted 2-dimethylanuno-1-N,N-dimethylcarbamoyl-1,3-diaza-1,3-butadienes 9. Ketones with enolizable hydrogen atoms undergo aldol reactions under these conditions. C-Acylimines 11b-11e, derived from benzil and substituted anilines, undergo [2 + 2] cycloaddition to dimethylcyanamide with subsequent ring opening to 1-(N,N-dimethylcarbamoyl)-2,3,4-triaryl-1,4-diaza-1,3-butadienes 15. 1,2-Diphenyl-2-(isopropylimino)ethanone (11a) reacts with dimethylcyanamide to give 2-dimethylamino-1-isopropyl-4,4-diphenyl-2-imidazolin-5-one (23) in a hitherto unknown multistep reaction. The structure of 23 was confirmed by an X-ray analysis. VCH Verlagsgesellschaft mbH, 1996.