183488-06-4

Basic information

• Product Name: (-)-2-(azepan-1-yl)ethyl 2-cyclohexyl-2-(thiophen-3-yl)acetate
• CAS NO: 183488-06-4
• Molecular Weight: 349.538
• Mol File: 183488-06-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (-)-2-(azepan-1-yl)ethyl 2-cyclohexyl-2-(thiophen-3-yl)acetate(CAS DataBase Reference)
• NIST Chemistry Reference: (-)-2-(azepan-1-yl)ethyl 2-cyclohexyl-2-(thiophen-3-yl)acetate(183488-06-4)
• EPA Substance Registry System: (-)-2-(azepan-1-yl)ethyl 2-cyclohexyl-2-(thiophen-3-yl)acetate(183488-06-4)

Safety Data

• Hazardous Substances Data: 183488-06-4(Hazardous Substances Data)

Upstream product

• 20603-00-3 2-(hexamethyleneimino)ethanol 
• 1233735-44-8 (S)-(-)-2-cyclohexyl-1-(1-phenyl-1H-imidazol-2-yl)-2-(thiophen-3-yl)ethanone 

Relevant articles and documents

Palladium-catalyzed asymmetric allylic alkylation of 2-acylimidazoles as ester enolate equivalents

A broad range of highly enantioenriched 2-acylimidazoles are synthesized by palladium-catalyzed decarboxylative asymmetric allylic alkylation (DAAA) of 2-imidazolo-substituted enol carbonates. The enantioenriched 2-acylimidazole products can easily be converted to the corresponding carboxylic acid, ester, amide, and ketone derivatives with complete retention of the enantiopurity. The synthetic utility of this new method is demonstrated in the short, efficient synthesis of cetiedil.