183589-14-2

Basic information

• Product Name: 2-ETHYNYL-4-METHYL-PHENOL
• Synonyms: 2-ETHYNYL-4-METHYL-PHENOL;Phenol, 2-ethynyl-4-methyl- (9CI)
• CAS NO: 183589-14-2
• Molecular Formula: C₉H₈O
• Molecular Weight: 132.15922
• Mol File: 183589-14-2.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 224.741°C at 760 mmHg
• Flash Point: 99.854°C
• Appearance: /
• Density: 1.093g/cm³
• Vapor Pressure: 0.06mmHg at 25°C
• Refractive Index: 1.575
• CAS DataBase Reference: 2-ETHYNYL-4-METHYL-PHENOL(CAS DataBase Reference)
• NIST Chemistry Reference: 2-ETHYNYL-4-METHYL-PHENOL(183589-14-2)
• EPA Substance Registry System: 2-ETHYNYL-4-METHYL-PHENOL(183589-14-2)

Safety Data

• Hazardous Substances Data: 183589-14-2(Hazardous Substances Data)

Usage

InChI:InChI=1/C9H8O/c1-3-8-6-7(2)4-5-9(8)10/h1,4-6,10H,2H3

Upstream product

• 6627-55-0 2-bromo-p-cresol 
• 1066-54-2 trimethylsilylacetylene 
• 175967-98-3 (2-bromo-4-methylphenoxy)(tert-butyl)dimethylsilane 
• 1431639-00-7 tert-butyl(dimethyl){4-methyl-2-[(trimethylsilyl)ethynyl]phenoxy} silane 
• 16188-57-1 2-iodo-4-methylphenol 
• 183589-03-9 4-methyl-2-(2-(trimethylsilyl)-ethynyl)phenol 

Downstream Products

• 1622092-52-7 2-(2-ethynyl-4-methylphenoxy)ethyl 4-bromobenzenesulfonate 
• 1622092-80-1 (E)-(6-methyl-2,3-dihydro-4H-chromen-4-ylidene)methyl 4-bromobenzenesulfonate 
• 54120-66-0 5-methyl-benzofuran-3-one 
• 1114386-17-2 2-ethynyl-4-methyl-6-o-tolylazo-phenol 
• 22772-29-8 5-methyl-2-(4-methylphenyl)benzofuran 

Relevant articles and documents

Copper-Catalyzed Asymmetric Diyne Cyclization via [1,2]-Stevens-Type Rearrangement for the Synthesis of Chiral Chromeno[3,4-c]pyrroles

Here, we report a copper-catalyzed asymmetric cascade cyclization/[1,2]-Stevens-type rearrangement via a non-diazo approach, leading to the practical and atom-economic assembly of various valuable chiral chromeno[3,4-c]pyrroles bearing a quaternary carbon

Catalytic Transformations of Alkynes into either α-Alkoxy or α-Aryl Enolates: Mannich Reactions by Cooperative Catalysis and Evidence for Nucleophile-Directed Chemoselectivity

The catalytic formation of gold enolates from alkynes, nitrones, and nucleophiles is described, and their Mannich reactions result in nucleophile-directed chemoselectivity through cooperative catalysis. For 1-alkyn-4-ols and 2-ethynylphenols, their gold-catalyzed nitrone oxidations afforded N-containing dihydrofuran-3(2H)-ones with syn selectivity. The mechanism involves the Mannich reactions of gold enolates with imines through an O-H-N hydrogen-bonding motif. For aryloxyethynes, their gold enolates react selectively with nitrones to deliver 3-alkylidenebenzofuran-2-ones, as controlled by a C-H-O hydrogen-bonding motif.

OPHTHALMIC LENS MATERIALS CONTAINING CHROMOPHORES THAT ABSORB BOTH UV AND SHORT WAVELENGTH VISIBLE LIGHT

Chromophores that absorb both UV and short wavelength visible light are disclosed. The chromophores are particularly suitable for use in intraocular lens materials.