183737-75-9

Basic information

• Product Name: 1,8(2H,5H)-Acridinedione, 3,4,6,7,9,10-hexahydro-3,3,6,6-tetramethyl-9-phenyl-10-(phenylmethyl)-
• CAS NO: 183737-75-9
• Molecular Formula: C30H33NO2
• Molecular Weight: 439.598
• Mol File: 183737-75-9.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 1,8(2H,5H)-Acridinedione, 3,4,6,7,9,10-hexahydro-3,3,6,6-tetramethyl-9-phenyl-10-(phenylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,8(2H,5H)-Acridinedione, 3,4,6,7,9,10-hexahydro-3,3,6,6-tetramethyl-9-phenyl-10-(phenylmethyl)-(183737-75-9)
• EPA Substance Registry System: 1,8(2H,5H)-Acridinedione, 3,4,6,7,9,10-hexahydro-3,3,6,6-tetramethyl-9-phenyl-10-(phenylmethyl)-(183737-75-9)

Safety Data

• Hazardous Substances Data: 183737-75-9(Hazardous Substances Data)

Upstream product

• 126-81-8 dimedone 
• 100-46-9 benzylamine 
• 100-51-6 benzyl alcohol 
• 889-31-6 5,5-dimethyl-3-benzylamino-2-cyclohexen-1-one 
• 100-52-7 benzaldehyde 

Downstream Products

• 2769-21-3 3,3,6,6-tetramethyl-9-phenyl-3,4,6,7,9,10-hexahydro-2H,5H-acridine-1,8-dione 

Relevant articles and documents

Synthesis of 1,8-Dioxo-decahydroacridine Derivatives via Ru-Catalyzed Acceptorless Dehydrogenative Multicomponent Reaction

A Ru-catalyzed acceptorless dehydrogenative multicomponent reaction has been developed. This reaction offers a cost-effective and simple operational strategy to synthesize biologically active 1,8-dioxodecahydroacridine derivatives. The protocol provides a wide range of substrate scope and various functional groups are also well tolerated under the reaction condition. To shed light on the mechanistic and kinetic study, some controlled experiments and deuterium labeling experiments were executed. A time-dependent product distribution experiment is also presented and the reaction scale-up is performed to highlight the practical utility of this strategy.

Cross-dehydrogenative regioselective Csp3-Csp2 coupling of enamino-ketones followed by rearrangement: An amazing formation route to acridine-1,8-dione derivatives

A new general method for the synthesis of acridine-1,8-diones through CDC coupling of enamino-ketones followed by rearrangement has been developed. This is a Cu(i) catalyzed procedure, based on the cross dehydrogenative coupling of the Csp3-H b

Magnetically recoverable, nanoscale-supported heteropoly acid catalyst for green synthesis of biologically active compounds in water

12-Tungstophosphoric acid supported on aerosil silica and silica-coated γ-Fe2O3 nanoparticles was prepared and characterized using transmission electron microscopy, scanning electron microscopy, and inductively coupled plasma atomic emission spectroscopy. The catalytic activity of the two prepared catalysts was compared in the synthesis of 1,8-dioxo-9,10- diaryldecahydroacridines in water. 12-Tungstophosphoric acid was highly dispersed on the silica-coated γ-Fe2O3 nanoparticles and showed higher activity and a higher reuse number compared with the acid supported on aerosil silica. The catalyst could be recovered simply by using an external magnetic field and could be reused several times without appreciable loss of its catalytic activity.